Difference between revisions of "Diffuse large B-cell lymphoma"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Diffuse_large_B_cell_lymphoma_-_cytology_low_mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = DLBCL - cytology. | ||
| Micro = | | Micro = large lymphoid cells (2-3x RBC), nucleolus | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = CD20+, CD10+, BCL6+, CD45 | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 14: | Line 14: | ||
| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = | | Site = [[Lymph node]] | ||
| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
| Line 25: | Line 25: | ||
| Prognosis = | | Prognosis = | ||
| Other = | | Other = | ||
| ClinDDx = }} | | ClinDDx = metastatic carcinoma, reactive lymphadenopathy, infective lymphadenopathy}} | ||
'''Diffuse large B cell lymphoma''', abbreviated '''DLBCL''', is a very common [[lymphoma]] with a poor prognosis. | '''Diffuse large B cell lymphoma''', abbreviated '''DLBCL''', is a very common [[lymphoma]] with a poor prognosis. | ||
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Features:<ref name=Ref_PCPBoD8_321>{{Ref PCPBoD8|321}}</ref><ref name=Ref_PBoD676>{{Ref PBoD|676 (???)}}</ref> | Features:<ref name=Ref_PCPBoD8_321>{{Ref PCPBoD8|321}}</ref><ref name=Ref_PBoD676>{{Ref PBoD|676 (???)}}</ref> | ||
*Large lymphoid cells: | *Large lymphoid cells: | ||
** | **2-4x the diameter of a small lymphocytes. | ||
**Marked cell-to-cell variation in size and shape. | **Marked cell-to-cell variation in size and shape. | ||
**Cytoplasm usually basophilic and moderate in abundance. | **Cytoplasm usually basophilic and moderate in abundance. | ||