Difference between revisions of "Melanocytic lesions"

Line 529:

*Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis.

*Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section.

*Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''.

*+/-Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''.

DDx:

*[[Melanoma in situ]] - especially on sun damaged skin ([[lentigo maligna]]).<ref name=pmid15953373>{{Cite journal | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref>

*[[Melanoma in situ]] - especially on [[solar elastosis|sun damaged skin]] ([[lentigo maligna]]).<ref name=pmid15953373>{{Cite journal | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref><ref name=pmid10911797>{{Cite journal | last1 = Edwards | first1 = SL. | last2 = Blessing | first2 = K. | title = Problematic pigmented lesions: approach to diagnosis. | journal = J Clin Pathol | volume = 53 | issue = 6 | pages = 409-18 | month = Jun | year = 2000 | doi = | PMID = 10911797 }}</ref>

*[[Malignant melanoma]] - especially on sun damaged skin ([[lentigo maligna melanoma]]).

*[[Compound melanocytic nevus]].

Difference between revisions of "Melanocytic lesions"

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@@ Line 529: / Line 529: @@
 *Drapping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis.
 *Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section.
-*Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''.
+*+/-Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''.
 DDx:
-*[[Melanoma in situ]] - especially on sun damaged skin ([[lentigo maligna]]).<ref name=pmid15953373>{{Cite journal  | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref>
+*[[Melanoma in situ]] - especially on [[solar elastosis|sun damaged skin]] ([[lentigo maligna]]).<ref name=pmid15953373>{{Cite journal  | last1 = Farrahi | first1 = F. | last2 = Egbert | first2 = BM. | last3 = Swetter | first3 = SM. | title = Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. | journal = J Cutan Pathol | volume = 32 | issue = 6 | pages = 405-12 | month = Jul | year = 2005 | doi = 10.1111/j.0303-6987.2005.00355.x | PMID = 15953373 }}</ref><ref name=pmid10911797>{{Cite journal  | last1 = Edwards | first1 = SL. | last2 = Blessing | first2 = K. | title = Problematic pigmented lesions: approach to diagnosis. | journal = J Clin Pathol | volume = 53 | issue = 6 | pages = 409-18 | month = Jun | year = 2000 | doi =  | PMID = 10911797 }}</ref>
 *[[Malignant melanoma]] - especially on sun damaged skin ([[lentigo maligna melanoma]]).
 *[[Compound melanocytic nevus]].