Difference between revisions of "Non-invasive breast carcinoma"

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**Architecture suggestive of DCIS - see ''[[Subtypes of DCIS]]''.
**Architecture suggestive of DCIS - see ''[[Subtypes of DCIS]]''.
*Nuclear changes:
*Nuclear changes:
**Nuclear enlargement - at least 2-3x size of RBC - '''key feature'''.
**Nuclear enlargement - at least 2-3x size of [[RBC]] - '''key feature'''.
***Compared to RBCs to grade DCIS - see ''[[Grading DCIS]]''.
***Compared to RBCs to grade DCIS - see ''[[Grading DCIS]]''.
****Compare sizes of nuclei if you cannot find RBCs.  
****Compare sizes of nuclei if you cannot find RBCs.  
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Graded 1-3 (low-high)<ref>URL: [http://surgpathcriteria.stanford.edu/breast/dcis/ http://surgpathcriteria.stanford.edu/breast/dcis/]. Accessed on: 4 August 2011.</ref> - compare lesional nuclei to one another.
Graded 1-3 (low-high)<ref>URL: [http://surgpathcriteria.stanford.edu/breast/dcis/ http://surgpathcriteria.stanford.edu/breast/dcis/]. Accessed on: 4 August 2011.</ref> - compare lesional nuclei to one another.
*Grade 1:  
*Grade 1:  
**Nuclei 2-3x size of RBC.
**Nuclei 2-3x size of [[RBC]].
**No necrosis.
**No necrosis.
*Grade 2:  
*Grade 2:  
**Nuclei 2-3x size of RBC.
**Nuclei 2-3x size of RBC.
**+/-Necrosis.
**+/-[[Necrosis]].
*Grade 3:
*Grade 3:
**Nuclei >3x size of RBC.
**Nuclei >3x size of RBC.
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