Difference between revisions of "Urothelium"
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*The urothelium may be "depleted", i.e. exist only of rare large cells on the basement membrane. | *The urothelium may be "depleted", i.e. exist only of rare large cells on the basement membrane. | ||
**This is known as ''clinging urothelial carcinoma in situ''.<ref>{{Ref Amin|2-55}}</ref> | **This is known as ''clinging urothelial carcinoma in situ''.<ref>{{Ref Amin|2-55}}</ref> | ||
===IHC=== | |||
Features:<ref>{{Cite journal | last1 = Lopez-Beltran | first1 = A. | last2 = Jimenez | first2 = RE. | last3 = Montironi | first3 = R. | last4 = Patriarca | first4 = C. | last5 = Blanca | first5 = A. | last6 = Menendez | first6 = CL. | last7 = Algaba | first7 = F. | last8 = Cheng | first8 = L. | title = Flat urothelial carcinoma in situ of the bladder with glandular differentiation. | journal = Hum Pathol | volume = 42 | issue = 11 | pages = 1653-9 | month = Nov | year = 2011 | doi = 10.1016/j.humpath.2010.12.024 | PMID = 21531007 }}</ref> | |||
*p53 +ve. | |||
*Ki-67 high. | |||
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