Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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m (→Benign: w) |
(→Non-malignant: +cellular angiofibroma) |
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| Line 304: | Line 304: | ||
*SMA +ve. | *SMA +ve. | ||
*S-100 -ve, | *S-100 -ve, | ||
==Cellular angiofibroma== | |||
===General=== | |||
*Rare. | |||
*Benign. | |||
*Probably related to [[spindle cell lipoma]] and [[mammary-type myofibroblastoma]].<ref name=pmid20852591>{{Cite journal | last1 = Flucke | first1 = U. | last2 = van Krieken | first2 = JH. | last3 = Mentzel | first3 = T. | title = Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma. | journal = Mod Pathol | volume = 24 | issue = 1 | pages = 82-9 | month = Jan | year = 2011 | doi = 10.1038/modpathol.2010.170 | PMID = 20852591 }}</ref> | |||
*Predominantly female. | |||
===Gross=== | |||
Features:<ref name=pmid20852591/> | |||
*Superficial. | |||
*Well-circumscribed. | |||
Classic location: | |||
*Vulva.<ref name=pmid20852591/> | |||
===Microscopic=== | |||
Features:<ref name=pmid20852591/> | |||
*Spindle cell lesion. | |||
*Many small-to-medium blood vessls. | |||
===IHC=== | |||
Features:<ref name=pmid20852591/> | |||
*CD34 ~50% of cases. | |||
*SMA ~41% of cases. | |||
*CD99 -ve. | |||
*EMA -ve. | |||
=Occasionally metastasizing= | =Occasionally metastasizing= | ||