Difference between revisions of "Endometrium"

Line 236:

*May be a cause of menorrhagia (heavy & long menses).

===Gross===

*Polypoid mass in the endometrial cavity.

Gross DDx:

*[[Secretory phase endometrium]].<ref name=pmid16873562/>

*Pedunculated [[uterine leiomyoma|leiomyoma]].

===Microscopic===

Features:<ref>~~URL: [http://www.pathologyoutlines.com/uterus~~.~~html#endopolyp http://www~~.~~pathologyoutlines~~.~~com~~/~~uterus~~.~~html#endopolyp]. Accessed on: 15 September 2011~~.</ref>

Features - diagnostic criteria:<ref name=pmid16873562>{{Cite journal | last1 = McCluggage | first1 = WG. | title = My approach to the interpretation of endometrial biopsies and curettings. | journal = J Clin Pathol | volume = 59 | issue = 8 | pages = 801-12 | month = Aug | year = 2006 | doi = 10.1136/jcp.2005.029702 | PMID = 16873562 | PMC = 1860448 }}</ref>

#Large blood vessels (muscular) - '''key feature'''.

#Fibrotic stroma - '''key feature'''.

#Polypoid shape - epithelium on three sides.

#*May not be seen... as polyp is fragmented on removal.

Glandular changes common:<ref name=pmid16873562/>

*Endometrial glands may be out of phase with surrounding [[endometrium]].

**Often proliferative.

*+/-Cystic dilation of glands/unusual shapes.

*+/-Focal crowding.

Notes:

#Apparently benign polyps should be examined closely at the surface for in situ & invasive malignancies.

#~~Endometrial glands may be out of phase with surrounding [[endometrium]].~~

#Stroma often cellular.

~~#*Often proliferative.~~

~~#+/-Cystic dilation of glands.~~

~~#Cellular stroma~~.

~~Other considerations -~~ DDx:

DDx:

*[[Adenofibroma]].

*[[Cervical polyp]].

*[[Cervical polyp]] - have endocervical mucosa.

*~~Pedunculated [[~~uterine ~~leiomyoma|leiomyoma]].~~

*Lower uterine segment - have endocervical epithelium and lack the thick-walled blood vessels.<ref name=pmid16873562/>

*[[Secretory phase endometrium]].

==Disordered proliferative endometrium==

Difference between revisions of "Endometrium"

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@@ Line 236: / Line 236: @@
 *May be a cause of menorrhagia (heavy & long menses).
+===Gross===
+*Polypoid mass in the endometrial cavity.
+Gross DDx:
+*[[Secretory phase endometrium]].<ref name=pmid16873562/>
+*Pedunculated [[uterine leiomyoma|leiomyoma]].
 ===Microscopic===
-Features:<ref>URL: [http://www.pathologyoutlines.com/uterus.html#endopolyp http://www.pathologyoutlines.com/uterus.html#endopolyp]. Accessed on: 15 September 2011.</ref>
+Features - diagnostic criteria:<ref name=pmid16873562>{{Cite journal  | last1 = McCluggage | first1 = WG. | title = My approach to the interpretation of endometrial biopsies and curettings. | journal = J Clin Pathol | volume = 59 | issue = 8 | pages = 801-12 | month = Aug | year = 2006 | doi = 10.1136/jcp.2005.029702 | PMID = 16873562 | PMC = 1860448 }}</ref>
 #Large blood vessels (muscular) - '''key feature'''.
 #Fibrotic stroma - '''key feature'''.
 #Polypoid shape - epithelium on three sides.
 #*May not be seen... as polyp is fragmented on removal.
+Glandular changes common:<ref name=pmid16873562/>
+*Endometrial glands may be out of phase with surrounding [[endometrium]].
+**Often proliferative.
+*+/-Cystic dilation of glands/unusual shapes.
+*+/-Focal crowding.
 Notes:
 #Apparently benign polyps should be examined closely at the surface for in situ & invasive malignancies.
-#Endometrial glands may be out of phase with surrounding [[endometrium]].
+#Stroma often cellular.
-#*Often proliferative.
-#+/-Cystic dilation of glands.
-#Cellular stroma.
-Other considerations - DDx:
+DDx:
 *[[Adenofibroma]].
-*[[Cervical polyp]].
+*[[Cervical polyp]] - have endocervical mucosa.
-*Pedunculated [[uterine leiomyoma|leiomyoma]].
+*Lower uterine segment - have endocervical epithelium and lack the thick-walled blood vessels.<ref name=pmid16873562/>
-*[[Secretory phase endometrium]].
 ==Disordered proliferative endometrium==