Difference between revisions of "Peripheral nerve sheath tumours"

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(→‎Schwannoma: subsections -- for subtypes)
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====Schwannoma subtypes====
====Schwannoma subtypes====
There are four:<ref name=pmid12792904>{{cite journal |author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM |title=The pathobiologic spectrum of Schwannomas |journal=Histol. Histopathol. |volume=18 |issue=3 |pages=925–34 |year=2003 |month=July |pmid=12792904 |doi= |url=}}</ref>
There are four:<ref name=pmid12792904>{{cite journal |author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM |title=The pathobiologic spectrum of Schwannomas |journal=Histol. Histopathol. |volume=18 |issue=3 |pages=925–34 |year=2003 |month=July |pmid=12792904 |doi= |url=}}</ref>
#Conventional schwannoma.
#Conventional schwannoma.  
#*Most common.
#Cellular schwannoma.  
#Cellular schwannoma.
#Plexiform schwannoma.  
#*May mimic [[MPNST]].
#**Images: [http://path.upmc.edu/cases/case518.html Cellular schwannoma (upmc.edu)].
#Plexiform schwannoma.
#*May mimic [[MPNST]] if cellular - esp. in childhood.
#**Images:
#***[http://commons.wikimedia.org/wiki/File:Plexiform_Schwannoma_2.jpg Plexiform schwannoma - low mag. (WC)].
#***[http://commons.wikimedia.org/wiki/File:Plexiform_Schwannoma_1.jpg Plexiform schwannoma - high mag. (WC)].
#Melanotic schwannoma.  
#Melanotic schwannoma.  
#*May be confused with [[melanoma]].
#*Psammomatous form (''psammomatous melanotic schwannoma'') associated with a heritable disorder ([[Carney complex]]).
#**Images: [http://path.upmc.edu/cases/case387.html Psammomatous melanotic schwannoma - several images (upmc.edu)].


Notes:
=====Conventional schwannoma=====
*Most common.
 
=====Cellular schwannoma=====
*May mimic [[MPNST]].
 
Images:
*[http://path.upmc.edu/cases/case518.html Cellular schwannoma (upmc.edu)].
 
=====Plexiform schwannoma=====
*May mimic [[MPNST]] if cellular - esp. in childhood.
 
Images:
*[http://commons.wikimedia.org/wiki/File:Plexiform_Schwannoma_2.jpg Plexiform schwannoma - low mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Plexiform_Schwannoma_1.jpg Plexiform schwannoma - high mag. (WC)].
 
=====Melanotic schwannoma=====
*May be confused with [[melanoma]].
*Psammomatous form (''psammomatous melanotic schwannoma'') associated with a heritable disorder ([[Carney complex]]).
 
Note:
*[[Carney complex]]:<ref name=pmid12792904/>
*[[Carney complex]]:<ref name=pmid12792904/>
**Cutaneous lentigines.
**Cutaneous lentigines.
**Myxomas (skin (subcutaneous), subcutanous, [[Atrial myxoma|heart]]).
**Myxomas (skin (subcutaneous), subcutanous, [[Atrial myxoma|heart]]).
**Endocrine neoplasms.
**Endocrine neoplasms.
Images:
*[http://path.upmc.edu/cases/case387.html Psammomatous melanotic schwannoma - several images (upmc.edu)].


===IHC===
===IHC===
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