Difference between revisions of "Endometrial carcinoma"

Line 162:

**Classically clear cells... but not always.

*Hobnail pattern -- apical cytoplasm > cytoplasm on basement membrane.

===IHC===

Features:<ref name=Ref_GP250>{{Ref GP|250}}</ref>

*p53 -ve usu. - unlike [[uterine serous carcinoma]].

*ER -ve.

*PR -ve.

Note:

*HNF1beta - not useful<ref name=pmid22495362>{{Cite journal | last1 = Fadare | first1 = O. | last2 = Liang | first2 = SX. | title = Diagnostic Utility of Hepatocyte Nuclear Factor 1-Beta Immunoreactivity in Endometrial Carcinomas: Lack of Specificity For Endometrial Clear Cell Carcinoma. | journal = Appl Immunohistochem Mol Morphol | volume = | issue = | pages = | month = Apr | year = 2012 | doi = 10.1097/PAI.0b013e31824973d1 | PMID = 22495362 }}</ref> - unlike for [[ovarian clear cell carcinoma]].

=See also=

Difference between revisions of "Endometrial carcinoma"

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@@ Line 162: / Line 162: @@
 **Classically clear cells... but not always.
 *Hobnail pattern -- apical cytoplasm > cytoplasm on basement membrane.
+===IHC===
+Features:<ref name=Ref_GP250>{{Ref GP|250}}</ref>
+*p53 -ve usu. - unlike [[uterine serous carcinoma]].
+*ER -ve.
+*PR -ve.
+Note:
+*HNF1beta - not useful<ref name=pmid22495362>{{Cite journal  | last1 = Fadare | first1 = O. | last2 = Liang | first2 = SX. | title = Diagnostic Utility of Hepatocyte Nuclear Factor 1-Beta Immunoreactivity in Endometrial Carcinomas: Lack of Specificity For Endometrial Clear Cell Carcinoma. | journal = Appl Immunohistochem Mol Morphol | volume =  | issue =  | pages =  | month = Apr | year = 2012 | doi = 10.1097/PAI.0b013e31824973d1 | PMID = 22495362 }}</ref> - unlike for [[ovarian clear cell carcinoma]].
 =See also=