Difference between revisions of "Inflammatory bowel disease"
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(→Crohn's disease: +ddx) |
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==Ulcerative colitis== | ==Ulcerative colitis== | ||
*Often abbreviated as ''UC''. | |||
===General=== | ===General=== | ||
* | *May be associated with ''toxic megacolon''. | ||
Epidemiology: | |||
*Associated with ''[[primary sclerosing cholangitis]]''. | *Associated with ''[[primary sclerosing cholangitis]]''. | ||
*[[Appendicitis]] is considered protective against UC.<ref name=pmid19685454>{{Cite journal | last1 = Beaugerie | first1 = L. | last2 = Sokol | first2 = H. | title = Appendicitis, not appendectomy, is protective against ulcerative colitis, both in the general population and first-degree relatives of patients with IBD. | journal = Inflamm Bowel Dis | volume = | issue = | pages = | month = Aug | year = 2009 | doi = 10.1002/ibd.21064 | PMID = 19685454 }}</ref><ref name=pmid19273505>{{Cite journal | last1 = Timmer | first1 = A. | last2 = Obermeier | first2 = F. | title = Reduced risk of ulcerative colitis after appendicectomy. | journal = BMJ | volume = 338 | issue = | pages = b225 | month = | year = 2009 | doi = | PMID = 19273505 }}</ref> | *[[Appendicitis]] is considered protective against UC.<ref name=pmid19685454>{{Cite journal | last1 = Beaugerie | first1 = L. | last2 = Sokol | first2 = H. | title = Appendicitis, not appendectomy, is protective against ulcerative colitis, both in the general population and first-degree relatives of patients with IBD. | journal = Inflamm Bowel Dis | volume = | issue = | pages = | month = Aug | year = 2009 | doi = 10.1002/ibd.21064 | PMID = 19685454 }}</ref><ref name=pmid19273505>{{Cite journal | last1 = Timmer | first1 = A. | last2 = Obermeier | first2 = F. | title = Reduced risk of ulcerative colitis after appendicectomy. | journal = BMJ | volume = 338 | issue = | pages = b225 | month = | year = 2009 | doi = | PMID = 19273505 }}</ref> | ||
*[[Smoking]] is protective; the opposite is true for Crohn's disease.<ref name=pmid19273505/> | *[[Smoking]] is protective; the opposite is true for [[Crohn's disease]].<ref name=pmid19273505/> | ||
===Gross=== | ===Gross=== | ||
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===Microscopic=== | ===Microscopic=== | ||
*Lack of granulomas. | Features: | ||
*Lack of [[granulomas]]. | |||
*No full wall-thickness inflammation. | *No full wall-thickness inflammation. | ||