Difference between revisions of "Endometrial carcinoma"
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===Microscopic=== | ===Microscopic=== | ||
Features - serous: | Features - serous: | ||
* | *Architecture: | ||
*#Papillary - common. | |||
*#*May be glomeruloid. | |||
*#Tubulocystic. | |||
*#Solid - uncommon. | |||
*Cytology: | |||
**Columnar cells. | **Columnar cells. | ||
**Cilia. | **Cilia. | ||
*[[Psammoma bodies]]. | |||
DDx: | DDx: | ||
*High-grade [[Endometrioid endometrial carcinoma]]. | *High-grade [[Endometrioid endometrial carcinoma]]. | ||
*[[Clear cell carcinoma of the endometrium]]. | *[[Clear cell carcinoma of the endometrium]] - usu. have less nuclear pleomorphism and less mitoses. | ||
===IHC=== | ===IHC=== | ||
*p53 +ve > 50% ''or'' 75%% of the tumour. | |||
*p16 +ve. | |||
==Clear cell carcinoma of the endometrium== | ==Clear cell carcinoma of the endometrium== | ||