Difference between revisions of "Neuromuscular pathology"
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**Women: 24-170 units/litre. | **Women: 24-170 units/litre. | ||
=Muscle structure/histology= | |||
===Macro to micro=== | ===Macro to micro=== | ||
Organization:<ref>URL: [http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg]. Accessed on: 25 October 2010.</ref> | Organization:<ref>URL: [http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg]. Accessed on: 25 October 2010.</ref> | ||
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***Same protein that that in implicated in [[ALS]] and [[frontotemporal dementia]]. | ***Same protein that that in implicated in [[ALS]] and [[frontotemporal dementia]]. | ||
=Inflammatory myopathy= | ==Inflammatory myopathy== | ||
DDx: | DDx: | ||
#Polymyositis. | #[[Polymyositis]]. | ||
#*Disease of adults. | #*Disease of adults. | ||
#Inclusion body myositis (IBM). | #[[Inclusion body myositis]] (IBM). | ||
#Dermatomyositis. | #[[Dermatomyositis]]. | ||
#*May be associated with malignancy. | #*May be associated with malignancy. | ||
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*Negative for [[tubuloreticular inclusions]]. | *Negative for [[tubuloreticular inclusions]]. | ||
==Trichinosis== | |||
:See ''[[Microorganisms]]''. | |||
Parasitic disease classically associated with consumption of uncooked pork. | |||
=Groups of disorders= | |||
==Limb-girdle muscular dystrophy== | ==Limb-girdle muscular dystrophy== | ||
===General=== | ===General=== | ||
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*Inflammatory myopathies. | *Inflammatory myopathies. | ||
==Mitochondrial disorders== | ==Mitochondrial disorders== | ||
===General=== | ===General=== | ||
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*Crystalloid inclusions.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q09-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q09-Ans.htm]. Accessed on: 26 October 2010.</ref> | *Crystalloid inclusions.<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q09-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q09-Ans.htm]. Accessed on: 26 October 2010.</ref> | ||
*"Ballooned" mitochondria; loss of cristae -- loss of membranous folds within mitochrondrion. | *"Ballooned" mitochondria; loss of cristae -- loss of membranous folds within mitochrondrion. | ||
==Type 2 fibre atrophy== | ==Type 2 fibre atrophy== | ||