Difference between revisions of "Gestational trophoblastic disease"
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m (replace most of pathconsult) |
m (→Clinical: replace pathconsultddx ref) |
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===General=== | ===General=== | ||
====Clinical==== | ====Clinical==== | ||
*Raised beta-hCG - but usually not has high as in choriocarcinoma.<ref name= | *Raised (serum) beta-hCG - but usually not has high as in choriocarcinoma; in ~70% < 1000 IU/L.<ref name=pmid19552948>{{Cite journal | last1 = Schmid | first1 = P. | last2 = Nagai | first2 = Y. | last3 = Agarwal | first3 = R. | last4 = Hancock | first4 = B. | last5 = Savage | first5 = PM. | last6 = Sebire | first6 = NJ. | last7 = Lindsay | first7 = I. | last8 = Wells | first8 = M. | last9 = Fisher | first9 = RA. | title = Prognostic markers and long-term outcome of placental-site trophoblastic tumours: a retrospective observational study. | journal = Lancet | volume = 374 | issue = 9683 | pages = 48-55 | month = Jul | year = 2009 | doi = 10.1016/S0140-6736(09)60618-8 | PMID = 19552948 }}</ref> | ||
*Derived from ''intermediate trophoblast''. | *Derived from ''intermediate trophoblast''. | ||
*Follows pregnancy. | |||
*Prognosis dependent on time of diagnosis from last pregnancy. | |||
**<48 months good prognosis.<ref name=pmid19552948/> | |||
====Epidemiology==== | ====Epidemiology==== | ||