Difference between revisions of "Myocarditis"

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#redirect [[Heart#Myocarditis]]
'''Myocarditis''' is inflammation of the [[heart]].
 
==General==
*Uncommon.
 
==Gross==
*Not apparent on gross.
 
Grossing:
*Requires 10 sections to exclude;<ref>KC. 1 October 2010.</ref> sections should include right ventricle and left ventricle.
**It is often missed with five.<ref name=pmid9559966>{{Cite journal  | last1 = Kubo | first1 = N. | last2 = Morimoto | first2 = S. | last3 = Hiramitsu | first3 = S. | last4 = Uemura | first4 = A. | last5 = Kimura | first5 = K. | last6 = Shimizu | first6 = K. | last7 = Hishida | first7 = H. | title = Feasibility of diagnosing chronic myocarditis by endomyocardial biopsy. | journal = Heart Vessels | volume = 12 | issue = 4 | pages = 167-70 | month =  | year = 1997 | doi =  | PMID = 9559966 }}</ref>
 
==Microscopic==
Features:
*Inflammation.
*Myocyte necrosis (disputed<ref name=pmid16449736>{{Cite journal  | last1 = Baughman | first1 = KL. | title = Diagnosis of myocarditis: death of Dallas criteria. | journal = Circulation | volume = 113 | issue = 4 | pages = 593-5 | month = Jan | year = 2006 | doi = 10.1161/CIRCULATIONAHA.105.589663 | PMID = 16449736 }}</ref>).
 
===Classification===
Classified by the inflammatory cells present:<ref name=emedicine1612533>[http://emedicine.medscape.com/article/1612533-overview http://emedicine.medscape.com/article/1612533-overview]</ref>
*Eosinophilic - ''hypersensitivity myocarditis'' - most common.
**May be assoc. with peripheral blood eosinophilia.<ref name=pmid20181108>{{cite journal |author=Amini R, Nielsen C |title=Eosinophilic myocarditis mimicking acute coronary syndrome secondary to idiopathic hypereosinophilic syndrome: a case report |journal=J Med Case Reports |volume=4 |issue= |pages=40 |year=2010 |pmid=20181108 |pmc=2830978 |doi=10.1186/1752-1947-4-40 |url=}}</ref>
*Lymphocytic - viral, autoimmune.
*Granulomatous - infectious, [[idiopathic granulomatous myocarditis|idiopathic]].
*Neutrophilic.
*Reperfusion (associated with myocardial infarction).
 
===Images===
*[http://commons.wikimedia.org/wiki/File:Viral_myocarditis_%281%29.JPG Myocarditis (viral) - 1 (WC)].
*[http://commons.wikimedia.org/wiki/File:Viral_myocarditis_%282%29.JPG Myocarditis (viral) - 2 (WC)].
*[http://jmedicalcasereports.com/content/4/1/40/figure/F5 Eosinophilic myocarditis (jmedicalcasereports.com)].<ref name=pmid20181108>{{cite journal |author=Amini R, Nielsen C |title=Eosinophilic myocarditis mimicking acute coronary syndrome secondary to idiopathic hypereosinophilic syndrome: a case report |journal=J Med Case Reports |volume=4 |issue= |pages=40 |year=2010 |pmid=20181108 |pmc=2830978 |doi=10.1186/1752-1947-4-40 |url=}}</ref>
 
==See also==
*[[Heart]].
 
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Heart]]

Revision as of 05:34, 21 July 2016

Myocarditis is inflammation of the heart.

General

  • Uncommon.

Gross

  • Not apparent on gross.

Grossing:

  • Requires 10 sections to exclude;[1] sections should include right ventricle and left ventricle.
    • It is often missed with five.[2]

Microscopic

Features:

  • Inflammation.
  • Myocyte necrosis (disputed[3]).

Classification

Classified by the inflammatory cells present:[4]

  • Eosinophilic - hypersensitivity myocarditis - most common.
    • May be assoc. with peripheral blood eosinophilia.[5]
  • Lymphocytic - viral, autoimmune.
  • Granulomatous - infectious, idiopathic.
  • Neutrophilic.
  • Reperfusion (associated with myocardial infarction).

Images

See also

References

  1. KC. 1 October 2010.
  2. Kubo, N.; Morimoto, S.; Hiramitsu, S.; Uemura, A.; Kimura, K.; Shimizu, K.; Hishida, H. (1997). "Feasibility of diagnosing chronic myocarditis by endomyocardial biopsy.". Heart Vessels 12 (4): 167-70. PMID 9559966.
  3. Baughman, KL. (Jan 2006). "Diagnosis of myocarditis: death of Dallas criteria.". Circulation 113 (4): 593-5. doi:10.1161/CIRCULATIONAHA.105.589663. PMID 16449736.
  4. http://emedicine.medscape.com/article/1612533-overview
  5. 5.0 5.1 Amini R, Nielsen C (2010). "Eosinophilic myocarditis mimicking acute coronary syndrome secondary to idiopathic hypereosinophilic syndrome: a case report". J Med Case Reports 4: 40. doi:10.1186/1752-1947-4-40. PMC 2830978. PMID 20181108. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830978/.