Difference between revisions of "Osteoid osteoma"

Revision as of 16:58, 25 August 2013

Osteoid osteoma, abbreviated OO, is benign primary bone tumour.

General

Benign bone lesion.

Clinical:^[1]

Extremely painful.
- Relieved by NSAIDs.

Gross

Bone: femur > tibia > spine > elsewhere.^[2]^[3]
Most common location (in bone): diaphysis.^[2]

Images:

Microscopic

Features:^[1]

Anastomosing bony trabeculae with:
- Variable mineralization.
  - Mineralization (calcium phosphate) = purple on H&E stain.
- Osteoblasts rimming.
  - Cells line-up at edge of bone.

Note:

Histomorphologically near identical/indistinguishable from osteoblastoma;^[5] one needs some history to make the diagnosis.

Images

Osteoid osteoma - low mag. (WC)
Osteoid osteoma - intermed. mag. (WC)
Osteoid osteoma - high mag. (WC)
Osteoid osteoma - very high mag. (WC)

www:

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BONE, RIGHT FEMUR, EXCISION:
- OSTEOID OSTEOMA.

Micro

The sections show anastomosing bony trabeculae with variable mineralization and osteoblastic rimming. Multinucleated osteoclasts are scattered through the lesion. Hemosiderin-laden macrophages are present. No osteocyte nuclear atypia is apparent. Mitotic activity is not apparent. The osteoid is not lace-like.

References

↑ ^1.0 ^1.1 Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 285. ISBN 978-0781740517.
↑ ^2.0 ^2.1 URL: http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html]. Accessed on: 7 May 2012.
↑ URL: http://www.radiologyassistant.nl/en/494e15cbf0d8d. Accessed on: 7 May 2012.
↑ URL: http://njms2.umdnj.edu/tutorweb/gross.htm. Accessed on: 7 May 2012.
↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 286. ISBN 978-0781740517.

[Ref_Sternberg4_285-1] 1.0 ^1.1 Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 285. ISBN 978-0781740517.

[uthscsa-2] 2.0 ^2.1 URL: http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html]. Accessed on: 7 May 2012.

[radiologyassistant-3] URL: http://www.radiologyassistant.nl/en/494e15cbf0d8d. Accessed on: 7 May 2012.

[4] URL: http://njms2.umdnj.edu/tutorweb/gross.htm. Accessed on: 7 May 2012.

[Ref_Sternberg4_286-5] Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Oberman, Harold A; Reuter, Victor E (2004). Sternberg's Diagnostic Surgical Pathology (4th ed.). Lippincott Williams & Wilkins. pp. 286. ISBN 978-0781740517.

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[2]

[3]

[4]

[5]

@@ Line 1: / Line 1: @@
-#redirect [[Chondro-osseous tumours#Osteoid osteoma]]
+'''Osteoid osteoma''', abbreviated '''OO''', is benign primary [[bone tumour]].
+==General==
+*Benign bone lesion.
+Clinical:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4|285}}</ref>
+*Extremely painful.
+**Relieved by [[NSAIDs]].
+==Gross==
+*Bone: femur > tibia > spine > elsewhere.<ref name=uthscsa>URL: http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html]. Accessed on: 7 May 2012.</ref><ref name=radiologyassistant>URL: [http://www.radiologyassistant.nl/en/494e15cbf0d8d http://www.radiologyassistant.nl/en/494e15cbf0d8d]. Accessed on: 7 May 2012.</ref>
+*Most common location (in bone): diaphysis.<ref name=uthscsa>URL: http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html]. Accessed on: 7 May 2012.</ref>
+Images:
+*[http://njms2.umdnj.edu/tutorweb/casegifs/ostostgross.jpg Osteoid osteoma - gross (umdnj.edu)].<ref>URL: [http://njms2.umdnj.edu/tutorweb/gross.htm http://njms2.umdnj.edu/tutorweb/gross.htm]. Accessed on: 7 May 2012.</ref>
+*[http://radiology.uthscsa.edu/CME/ELTXT/OOT/treatment.html Osteoid osteoma (uthscsa.edu)].
+==Microscopic==
+Features:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4|285}}</ref>
+*Anastomosing bony [[trabeculae]] with:
+**Variable mineralization.
+***Mineralization (calcium '''p'''hosphate) = '''p'''urple on [[H&E stain]].
+**Osteoblasts rimming.
+***Cells line-up at edge of bone.
+Note:
+*Histomorphologically near identical/indistinguishable from ''[[osteoblastoma]]'';<ref name=Ref_Sternberg4_286>{{Ref Sternberg4|286}}</ref> one needs some history to make the diagnosis.
+===Images===
+<gallery>
+Image:Osteoid_osteoma_-_low_mag.jpg | Osteoid osteoma - low mag. (WC)
+Image:Osteoid osteoma - intermed mag.jpg | Osteoid osteoma - intermed. mag. (WC)
+Image:Osteoid_osteoma_-_high_mag.jpg | Osteoid osteoma - high mag. (WC)
+Image:Osteoid osteoma - very high mag.jpg | Osteoid osteoma - very high mag. (WC)
+</gallery>
+www:
+*[http://library.med.utah.edu/WebPath/COW/COW211.html Osteoid osteoma - CT scan (med.utah.edu)].
+*[http://www.sciencephoto.com/images/imagePopUpDetails.html?pop=1&id=700030210&pviewid=&country=67&search=gschmeissners&matchtype=FUZZY Osteoid osteoma (sciencephoto.com)].
+==Sign out==
+<pre>
+BONE, RIGHT FEMUR, EXCISION:
+- OSTEOID OSTEOMA.
+</pre>
+===Micro===
+The sections show anastomosing bony trabeculae with variable mineralization and osteoblastic rimming. Multinucleated osteoclasts are scattered through the lesion. Hemosiderin-laden macrophages are present. No osteocyte nuclear atypia is apparent. Mitotic activity is not apparent. The osteoid is not lace-like.
+==See also==
+*[[Chondro-osseous tumours]].
+*[[Bone]].
+==References==
+{{Reflist|2}}
 [[Category:Diagnosis]]
+[[Category:Chondro-osseous tumours]]

Difference between revisions of "Osteoid osteoma"

Revision as of 16:58, 25 August 2013

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