Difference between revisions of "Dermal scar"

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#redirect [[Non-malignant_skin_disease#Cicatrix]]
'''Dermal scar''', also simply '''scar''', is commonly seen in [[dermatopathology]]. It is also known a '''cicatrix'''.
 
==General==
*Previous surgery, biopsy, trauma.
 
==Microscopic==
Features:
*Loss of dermal papilla.
*Dense collagen - fibers run parallel to the dermal-epidermal (DE) junction<ref name=Ref_Derm499>{{Ref Derm|499}}</ref> - '''key feature'''.
*Loss of adnexal structures.
 
Other feature:
*Thin-walled blood vessels.
**Described as running perpendicular to the surface<ref name=Ref_Derm499>{{Ref Derm|499}}</ref> - this may not be apparent.
 
Note:
*There should not be any nuclear hyperchromasia or pleomorphism.<ref name=Ref_Derm479>{{Ref Derm|479}}</ref>
 
DDx:
*[[Malignant melanoma]], desmoplastic-neurotropic type - nuclear pleomorphism and/or hyperchromasia; may be focal.<ref name=Ref_Derm479>{{Ref Derm|479}}</ref>
*[[Dermatofibroma]].
*Desmoplastic [[Spitz nevus]].
*Sclerosing [[blue nevus]].
 
===Image===
<gallery>
Image:ScarHistology.JPG | Scar. (WC)
</gallery>
==IHC==
*S100 focal/scattered +ve.
**Desmoplastic melanoma strong +ve.
*HMB-45 -ve.
**Sclerosing blue nevus +ve.
 
==Sign out==
<pre>
SKIN, LOWER MID BACK, RE-EXCISION:
- DERMAL SCAR.
- SOLAR ELASTOSIS.
</pre>
 
===Micro===
The sections show skin with a dermis with dense collagen fibres that run parallel to the skin surface without adnexal structures.  The overlying dermal-epidermis interface lacks the typical undulation.
 
==See also==
*[[Non-malignant skin disease]].
*[[Dermatopathology]].
 
[[Category:Diagnosis]]
[[Category:Dermatopathology]]
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