Difference between revisions of "Intranodal palisaded myofibroblastoma"
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#spindle cells with nuclear palisading | #spindle cells with nuclear palisading | ||
#RBC extravasation/hemorrhage. | #RBC extravasation/hemorrhage. | ||
#Amianthoid fibers | #Amianthoid fibers - blood vessel surrounded by collagen with peripheral spokes.<ref name=pmid1918406>{{Cite journal | last1 = Bigotti | first1 = G. | last2 = Coli | first2 = A. | last3 = Mottolese | first3 = M. | last4 = Di Filippo | first4 = F. | title = Selective location of palisaded myofibroblastoma with amianthoid fibres. | journal = J Clin Pathol | volume = 44 | issue = 9 | pages = 761-4 | month = Sep | year = 1991 | doi = | PMID = 1918406 }}</ref> | ||
#intracellular and extracellular fuchsinophilic bodies that stain positive for smooth muscle actin. | #intracellular and extracellular fuchsinophilic bodies that stain positive for smooth muscle actin. | ||
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*[[Schwannoma]]. | *[[Schwannoma]]. | ||
Images: | |||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802163636511 IPM (surgicalpathologyatlas.com)]. | *[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802163636511 IPM (surgicalpathologyatlas.com)]. | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC496726/figure/F4/ Amianthoid fibers (nih.gov)].<ref name=pmid1918406>{{Cite journal | last1 = Bigotti | first1 = G. | last2 = Coli | first2 = A. | last3 = Mottolese | first3 = M. | last4 = Di Filippo | first4 = F. | title = Selective location of palisaded myofibroblastoma with amianthoid fibres. | journal = J Clin Pathol | volume = 44 | issue = 9 | pages = 761-4 | month = Sep | year = 1991 | doi = | PMID = 1918406 }}</ref> | |||
==IHC== | ==IHC== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Lymph node pathology]] | [[Category:Lymph node pathology]] | ||
Revision as of 03:33, 4 October 2011
Intranodal palisaded myofibroblastoma, abbreviated IPM, is a rare tumour that classically presents as an inguinal mass.[1]
General
- Rare.
- Male:female = 2:1.
- Adults - middle age.
Microscopic
Features:
- Rim of peripheral lymphoid tissue.
- spindle cells with nuclear palisading
- RBC extravasation/hemorrhage.
- Amianthoid fibers - blood vessel surrounded by collagen with peripheral spokes.[2]
- intracellular and extracellular fuchsinophilic bodies that stain positive for smooth muscle actin.
DDx:
Images:
IHC
- SMA +ve.
- Cyclin D1 +ve.
Other:
- S100 -ve
- Excludes schwannoma.
- GFAP -ve.
- CD34 -ve.
- Desmin -ve
- Ki-67 - low.
See also
References
- ↑ Nguyen, T.; Eltorky, MA. (Feb 2007). "Intranodal palisaded myofibroblastoma.". Arch Pathol Lab Med 131 (2): 306-10. doi:10.1043/1543-2165(2007)131[306:IPM]2.0.CO;2. PMID 17284119.
- ↑ 2.0 2.1 Bigotti, G.; Coli, A.; Mottolese, M.; Di Filippo, F. (Sep 1991). "Selective location of palisaded myofibroblastoma with amianthoid fibres.". J Clin Pathol 44 (9): 761-4. PMID 1918406.