Difference between revisions of "Extramammary Paget disease"
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'''Extramammary Paget disease''' is a skin disease. As the name suggests, there is also a [[Paget disease of the breast]]. | '''Extramammary Paget disease''', abbreviated '''EMPD''', is a skin disease. As the name suggests, there is also a [[Paget disease of the breast]]. | ||
There is also a ''[[Paget disease of the bone]]'' - just to make things confusing. This is dealt with in the ''[[bone]]'' article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article | There is also a ''[[Paget disease of the bone]]'' - just to make things confusing. This is dealt with in the ''[[bone]]'' article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article | ||
Revision as of 05:30, 27 August 2011
Extramammary Paget disease, abbreviated EMPD, is a skin disease. As the name suggests, there is also a Paget disease of the breast.
There is also a Paget disease of the bone - just to make things confusing. This is dealt with in the bone article and has nothing (from a pathologic perspective) to do with the Paget disease discussed in this article
General
- Usually not associated with malignancy, unlike the Paget disease of the breast - important difference.
- Classically seen in the vulva.
- May afflict penis.[1]
Microscopic
Features:
- Epitheliod morphology (round/ovoid).
- Cells nested or single.
- Clear/pale cytoplasm key feature - may also be eosinophilic.
- Large nucleoli.
Images:
DDx
- Benign Toker cell hyperplasia.
- Malignant melanoma.
- Bowen disease.
- Nipple (duct) adenoma (clinical DDx).
See also
References
- ↑ Ekwueme, KC.; Zakhour, HD.; Parr, NJ. (2009). "Extramammary Paget's disease of the penis: a case report and review of the literature.". J Med Case Reports 3: 4. doi:10.1186/1752-1947-3-4. PMID 19126202.