Difference between revisions of "Residual cancer burden index"
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==Definition== | ==Definition== | ||
The [[RCB index]] is defined as: | The [[RCB index]] is defined as:<ref name=pmid17785706>{{cite journal |authors=Symmans WF, Peintinger F, Hatzis C, Rajan R, Kuerer H, Valero V, Assad L, Poniecka A, Hennessy B, Green M, Buzdar AU, Singletary SE, Hortobagyi GN, Pusztai L |title=Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy |journal=J Clin Oncol |volume=25 |issue=28 |pages=4414–22 |date=October 2007 |pmid=17785706 |doi=10.1200/JCO.2007.10.6823 |url=}}</ref> | ||
:<math>RCB = 1.4 \ ( f_{inv} \ d_{prim} )^ {0.17} + \lbrack{ \ 4 \ (1 - 0.75^{LN}) d_{met}} \rbrack ^{0.17}</math> | :<math>RCB = 1.4 \ ( f_{inv} \ d_{prim} )^ {0.17} + \lbrack{ \ 4 \ (1 - 0.75^{LN}) d_{met}} \rbrack ^{0.17}</math> | ||
Revision as of 23:40, 15 October 2024
Residual cancer burden index, abbreviated RCB, is an empirical predictor of outcome in breast cancer in the post-neoadjuvant therapy setting.[1]
Definition
The RCB index is defined as:[2]
See also
References
- ↑ Yau C, Osdoit M, van der Noordaa M, Shad S, Wei J, de Croze D, Hamy AS, Laé M, Reyal F, Sonke GS, Steenbruggen TG, van Seijen M, Wesseling J, Martín M, Del Monte-Millán M, López-Tarruella S, Boughey JC, Goetz MP, Hoskin T, Gould R, Valero V, Edge SB, Abraham JE, Bartlett JM, Caldas C, Dunn J, Earl H, Hayward L, Hiller L, Provenzano E, Sammut SJ, Thomas JS, Cameron D, Graham A, Hall P, Mackintosh L, Fan F, Godwin AK, Schwensen K, Sharma P, DeMichele AM, Cole K, Pusztai L, Kim MO, van 't Veer LJ, Esserman LJ, Symmans WF (January 2022). "Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients". Lancet Oncol 23 (1): 149–160. doi:10.1016/S1470-2045(21)00589-1. PMID 34902335.
- ↑ Symmans WF, Peintinger F, Hatzis C, Rajan R, Kuerer H, Valero V, Assad L, Poniecka A, Hennessy B, Green M, Buzdar AU, Singletary SE, Hortobagyi GN, Pusztai L (October 2007). "Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy". J Clin Oncol 25 (28): 4414–22. doi:10.1200/JCO.2007.10.6823. PMID 17785706.