Olfactory neuroblastoma: Difference between revisions
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Jensflorian (talk | contribs) →Microscopic: Images added |
Jensflorian (talk | contribs) →IHC: S-100 in neuronal ONB |
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==IHC== | ==IHC== | ||
*S-100: | *S-100: | ||
**Small round cells -ve. | |||
**Sustentacular cells +ve. | **Sustentacular cells +ve. | ||
** | ***Neuronal ONB subtype is enriched for the presence of S100 sustentacular cells. | ||
*[[Neuroendocrine markers]] +ve (CD56, synaptophysin). | *[[Neuroendocrine markers]] +ve (CD56, synaptophysin). | ||
**lower expression of neuroendocrine markers in IDH2 mutant tumors. | **lower expression of neuroendocrine markers in IDH2 mutant tumors. | ||