Difference between revisions of "Leydig cell hyperplasia"
Jump to navigation
Jump to search
(→Gross) |
|||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = abundant Leydig cells interspersed between seminiferous tubules with only Sertoli cells, Leydig cells do not displace or compress the seminiferous tubules | |||
| Subtypes = | |||
| LMDDx = [[Leydig cell tumour]], [[testicular adrenal rest tumour]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[testis]], [[ovary]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = hypoechoic lesions on ultrasound, often multiple | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Leydig cell hyperplasia''' is an uncommon benign [[pathology]] of the [[testis]].<ref name=pmid12540460>{{Cite journal | last1 = Carucci | first1 = LR. | last2 = Tirkes | first2 = AT. | last3 = Pretorius | first3 = ES. | last4 = Genega | first4 = EM. | last5 = Weinstein | first5 = SP. | title = Testicular Leydig's cell hyperplasia: MR imaging and sonographic findings. | journal = AJR Am J Roentgenol | volume = 180 | issue = 2 | pages = 501-3 | month = Feb | year = 2003 | doi = 10.2214/ajr.180.2.1800501 | PMID = 12540460 }}</ref> It may be seen in the [[ovary]]. | '''Leydig cell hyperplasia''' is an uncommon benign [[pathology]] of the [[testis]].<ref name=pmid12540460>{{Cite journal | last1 = Carucci | first1 = LR. | last2 = Tirkes | first2 = AT. | last3 = Pretorius | first3 = ES. | last4 = Genega | first4 = EM. | last5 = Weinstein | first5 = SP. | title = Testicular Leydig's cell hyperplasia: MR imaging and sonographic findings. | journal = AJR Am J Roentgenol | volume = 180 | issue = 2 | pages = 501-3 | month = Feb | year = 2003 | doi = 10.2214/ajr.180.2.1800501 | PMID = 12540460 }}</ref> It may be seen in the [[ovary]]. | ||
Revision as of 20:41, 19 May 2016
| Leydig cell hyperplasia | |
|---|---|
| Diagnosis in short | |
|
| |
| LM | abundant Leydig cells interspersed between seminiferous tubules with only Sertoli cells, Leydig cells do not displace or compress the seminiferous tubules |
| LM DDx | Leydig cell tumour, testicular adrenal rest tumour |
| Site | testis, ovary |
|
| |
| Prevalence | rare |
| Radiology | hypoechoic lesions on ultrasound, often multiple |
| Prognosis | benign |
Leydig cell hyperplasia is an uncommon benign pathology of the testis.[1] It may be seen in the ovary.
General
- May be seen in the context of Klinefelter syndrome.[2]
Gross
- Unremarkable gross appearance
Note:
- Hypoechoic lesions on ultrasound - often multiple, small.[2]
Microscopic
Features:
- Abundant Leydig cells interspersed between seminiferous tubules with only Sertoli cells.
- Do not displace or compress the seminiferous tubules.
Note:
- May form nodules up to 6 mm.[1]
DDx:
See also
References
- ↑ 1.0 1.1 Carucci, LR.; Tirkes, AT.; Pretorius, ES.; Genega, EM.; Weinstein, SP. (Feb 2003). "Testicular Leydig's cell hyperplasia: MR imaging and sonographic findings.". AJR Am J Roentgenol 180 (2): 501-3. doi:10.2214/ajr.180.2.1800501. PMID 12540460.
- ↑ 2.0 2.1 Sterbis, J.; E-Nunu, T. (2015). "Leydig cell hyperplasia in the setting of Klinefelter syndrome.". BMJ Case Rep 2015. doi:10.1136/bcr-2015-209805. PMID 26209412.