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Difference between revisions of "Colon"
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→Melanosis coli: tweak format
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*Thought to be caused by the higher wall tension of cecum (due to larger diameter) and result from (intermittent) venous occulsion/focal dilation of vessels.<ref name=Ref_PBoD854>{{Ref PBoD|854}}</ref> | *Thought to be caused by the higher wall tension of cecum (due to larger diameter) and result from (intermittent) venous occulsion/focal dilation of vessels.<ref name=Ref_PBoD854>{{Ref PBoD|854}}</ref> | ||
== | ==Pseudomelanosis coli== | ||
*AKA '' | *AKA ''melanosis coli''.<ref>URL: [http://www.medicinenet.com/melanosis_coli/article.htm http://www.medicinenet.com/melanosis_coli/article.htm]. Accessed on: 4 March 2011.</ref> | ||
*''Not melanin'' as the name suggests; it is actually lipofuscin (in macrophages).<ref name=pmid18666316>{{cite journal |author=Freeman HJ |title="Melanosis" in the small and large intestine |journal=World J. Gastroenterol. |volume=14 |issue=27 |pages=4296-9 |year=2008 |month=July |pmid=18666316 |doi= |url=http://www.wjgnet.com/1007-9327/14/4296.asp}}</ref> | ===General=== | ||
*''Not melanin'' as the name ''melanosis coli'' suggests; it is actually lipofuscin (in macrophages).<ref name=pmid18666316>{{cite journal |author=Freeman HJ |title="Melanosis" in the small and large intestine |journal=World J. Gastroenterol. |volume=14 |issue=27 |pages=4296-9 |year=2008 |month=July |pmid=18666316 |doi= |url=http://www.wjgnet.com/1007-9327/14/4296.asp}}</ref> | |||
*Endoscopist may see brown pigmentation of mucosa and suspect the diagnosis. | *Endoscopist may see brown pigmentation of mucosa and suspect the diagnosis. | ||
===Epidemiology=== | ====Epidemiology==== | ||
*Classically associated with anthracene containing laxative (e.g. Senokot) use and herbal remedies.<ref name=pmid18666316/> | *Classically associated with anthracene containing laxative (e.g. Senokot) use and herbal remedies.<ref name=pmid18666316/> | ||
=== | ===Gross=== | ||
*Brown pigmentation of the mucosa. | *Brown pigmentation of the mucosa. | ||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Melanosis_coli.jpg Melanosis coli - endoscopic image (WC)]. | |||
===Microscopic=== | |||
Features: | |||
*Typically more prominent in the cecum and proximal colon.<ref name=pmid18666316/> | *Typically more prominent in the cecum and proximal colon.<ref name=pmid18666316/> | ||