Difference between revisions of "Ovarian metastasis"

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An '''ovarian metastasis''' (also '''ovary with metastatic disease''') is [[cancer]] in the [[ovary]] that arose elsewhere and spread to the ovary.
An '''ovarian metastasis''' (also '''ovary with metastatic disease''' and '''metastatic ovarian disease''') is [[cancer]] in the [[ovary]] that arose elsewhere and spread to the ovary.


==Generally==
==Generally==

Revision as of 05:23, 28 January 2016

An ovarian metastasis (also ovary with metastatic disease and metastatic ovarian disease) is cancer in the ovary that arose elsewhere and spread to the ovary.

Generally

Common extramuellerian metastatic tumours:

Gross

Features favouring metastatic mucinous carcinoma (from the GI tract) over primary ovarian mucinous carcinoma:[1]

  • Bilaterality - both ovaries involved.
  • Small unilateral tumour size.
    • <10 cm suggests metastasis.
    • >13 cm = ovarian primary.

Microscopic

Features:

Image

IHC

Ovarian tumours:

  • Dipeptidase 1 (DPEP1) +ve.[2]
  • CK7 +ve.

See also

References

  1. Yemelyanova, AV.; Vang, R.; Judson, K.; Wu, LS.; Ronnett, BM. (Jan 2008). "Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification.". Am J Surg Pathol 32 (1): 128-38. doi:10.1097/PAS.0b013e3180690d2d. PMID 18162780.
  2. Okamoto, T.; Matsumura, N.; Mandai, M.; Oura, T.; Yamanishi, Y.; Horiuchi, A.; Hamanishi, J.; Baba, T. et al. (Feb 2011). "Distinguishing primary from secondary mucinous ovarian tumors: an algorithm using the novel marker DPEP1.". Mod Pathol 24 (2): 267-76. doi:10.1038/modpathol.2010.204. PMID 21076463.