Difference between revisions of "Fibrosing pleuritis"
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**Spindle cells. | **Spindle cells. | ||
**Moderate cellularity. | **Moderate cellularity. | ||
*No [[necrosis]]. | *No [[necrosis]].<ref name=pmid9704618/> | ||
*Inflammation - lymphocytes.<ref name=pmid3166932/> | *Inflammation - lymphocytes.<ref name=pmid3166932/> | ||
DDx:<ref name=pmid15559051>{{Cite journal | last1 = Corson | first1 = JM. | title = Pathology of mesothelioma. | journal = Thorac Surg Clin | volume = 14 | issue = 4 | pages = 447-60 | month = Nov | year = 2004 | doi = 10.1016/j.thorsurg.2004.06.007 | PMID = 15559051 }}</ref> | DDx:<ref name=pmid15559051>{{Cite journal | last1 = Corson | first1 = JM. | title = Pathology of mesothelioma. | journal = Thorac Surg Clin | volume = 14 | issue = 4 | pages = 447-60 | month = Nov | year = 2004 | doi = 10.1016/j.thorsurg.2004.06.007 | PMID = 15559051 }}</ref> | ||
*[[Mesothelioma]], desmoplastic. | *[[Mesothelioma]], desmoplastic. | ||
* | |||
Note: | |||
*Some say mesothelioma should '''not''' be diagnosed on core biopsy.<ref name=ultrapathorg>URL: [http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html]. Accessed on: 20 February 2012.</ref> | |||
==IHC== | ==IHC== | ||
Revision as of 17:58, 2 September 2015
Fibrosing pleuritis, also fibrous pleurisy, is an uncommon benign condition that mimics malignant mesothelioma.
It may be referred to as cryptogenic bilateral fibrosing pleuritis, if it is bilateral.
General
- Benign.
- No asbestos exposure.[1]
Clinical:[1]
- Pleural thickening on imaging.
- Pleural effusion.
Gross
- Pleural thickening associated with a pleural effusion.
Microscopic
Features:[2]
DDx:[4]
- Mesothelioma, desmoplastic.
Note:
- Some say mesothelioma should not be diagnosed on core biopsy.[2]
IHC
- p53 -ve/+ve.
- More common in mesothelioma.[3]
See also
References
- ↑ 1.0 1.1 1.2 Buchanan, DR.; Johnston, ID.; Kerr, IH.; Hetzel, MR.; Corrin, B.; Turner-Warwick, M. (Apr 1988). "Cryptogenic bilateral fibrosing pleuritis.". Br J Dis Chest 82 (2): 186-93. PMID 3166932.
- ↑ 2.0 2.1 URL: http://www.ultrapath.org/oldsite/uscap/uscap05/meso1.html. Accessed on: 20 February 2012.
- ↑ 3.0 3.1 Mangano, WE.; Cagle, PT.; Churg, A.; Vollmer, RT.; Roggli, VL. (Aug 1998). "The diagnosis of desmoplastic malignant mesothelioma and its distinction from fibrous pleurisy: a histologic and immunohistochemical analysis of 31 cases including p53 immunostaining.". Am J Clin Pathol 110 (2): 191-9. PMID 9704618.
- ↑ Corson, JM. (Nov 2004). "Pathology of mesothelioma.". Thorac Surg Clin 14 (4): 447-60. doi:10.1016/j.thorsurg.2004.06.007. PMID 15559051.