Difference between revisions of "Micropapillary urothelial carcinoma"
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==General== | ==General== | ||
*Aggressive behaviour.<ref name=pmid21080874/> | *Aggressive behaviour.<ref name=pmid21080874/> | ||
*Typically presents with [[hematuria]].<ref name=pmid25673582>{{Cite journal | last1 = Chatterjee | first1 = D. | last2 = Das | first2 = A. | last3 = Radotra | first3 = BD. | title = Invasive micropapillary carcinoma of urinary bladder: a clinicopathological study. | journal = Indian J Pathol Microbiol | volume = 58 | issue = 1 | pages = 2-6 | month = | year = | doi = 10.4103/0377-4929.151153 | PMID = 25673582 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid21080874/> | Features:<ref name=pmid21080874/> | ||
*Micropapillae. | *Micropapillae. | ||
**Quantity of micropapillary (percentage) is variable.<ref name=pmid25673582/> | |||
*Conventional [[urothelial carcinoma]] (typical). | |||
DDx: | |||
*[[Metastasis]] (breast, ovary, lung, pancreas, salivary gland). | |||
===Images=== | ===Images=== | ||
| Line 17: | Line 23: | ||
Image: Urothelial carcinoma with micropapillary features -- very high mag.jpg | UCCMPF - very high mag. | Image: Urothelial carcinoma with micropapillary features -- very high mag.jpg | UCCMPF - very high mag. | ||
</gallery> | </gallery> | ||
==IHC== | |||
Features: | |||
*CK7 +ve.<ref name=pmid25673582/> | |||
*CK20 +ve/-ve.<ref name=pmid25673582/> | |||
*EMA +ve.<ref name=pmid25673582/> | |||
*HER2 +ve/-ve.<ref name=pmid25673582/> | |||
==Sign out== | |||
*Report percentage of micropapillary pattern - suggested.{{fact}} | |||
==See also== | ==See also== | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Genitourinary pathology]] | [[Category:Genitourinary pathology]] | ||
Revision as of 01:54, 15 June 2015
Micropapillary urothelial carcinoma is an aggressive variant of urothelial carcinoma.[1]
General
Microscopic
Features:[1]
- Micropapillae.
- Quantity of micropapillary (percentage) is variable.[2]
- Conventional urothelial carcinoma (typical).
DDx:
- Metastasis (breast, ovary, lung, pancreas, salivary gland).
Images
UCCMPF - low mag.
UCCMPF - low mag.
UCCMPF - intermed. mag.
UCCMPF - high mag.
UCCMPF - high mag.
UCCMPF - very high mag.
IHC
Features:
Sign out
- Report percentage of micropapillary pattern - suggested.[citation needed]
See also
References
- ↑ 1.0 1.1 1.2 Compérat, E.; Roupret, M.; Yaxley, J.; Reynolds, J.; Varinot, J.; Ouzaïd, I.; Cussenot, O.; Samaratunga, H. (Dec 2010). "Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 cases.". Pathology 42 (7): 650-4. doi:10.3109/00313025.2010.522173. PMID 21080874.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Chatterjee, D.; Das, A.; Radotra, BD.. "Invasive micropapillary carcinoma of urinary bladder: a clinicopathological study.". Indian J Pathol Microbiol 58 (1): 2-6. doi:10.4103/0377-4929.151153. PMID 25673582.