Difference between revisions of "Nasopharyngeal angiofibroma"

From Libre Pathology
Jump to navigation Jump to search
(tweak)
(→‎Images: more images)
Line 46: Line 46:
===Images===  
===Images===  
<gallery>
<gallery>
Image:Nasopharyngeal_angiofibroma_-_intermed_mag.jpg | Nasopharyngeal angiofibroma - intermed. mag. (WC)
Image: Nasopharyngeal angiofibroma - intermed mag.jpg | Intermed. mag.
Image:Nasopharyngeal_angiofibroma_-_2_-_high_mag.jpg | Nasopharyngeal angiofibroma - high mag. (WC)
Image: Nasopharyngeal angiofibroma - high mag.jpg | High mag.
Image: Nasopharyngeal angiofibroma - very high mag.jpg | Very high mag.
</gallery>
<gallery>
Image: Nasopharyngeal angiofibroma - 2 - high mag.jpg | High mag.
</gallery>
</gallery>



Revision as of 22:28, 15 November 2014

Nasopharyngeal angiofibroma
Diagnosis in short

Nasopharyngeal angiofibroma. H&E stain.

LM fibroblastic cells with plump (near cuboidal) nuclei, fibrous stroma, abundant capillaries
Site head and neck - nasopharynx

Clinical history male, adolescents young to adults, frequent nose bleeds
Prevalence uncommon
Prognosis benign
Treatment surgical resection

Nasopharyngeal angiofibroma is a benign lesion of the head and neck.

General

  • Classically adolescent males with recurrent nose bleeds.
    • Age range 8-41 in one series of 162 cases.[1]
  • Can be subtyped by location into three groups.[2]

Microscopic

Features:[3]

  • Fibroblastic cells with plump (near cuboidal) nuclei.
  • Fibrous stroma.
  • Abundant capillaries.

Images

See also

References

  1. Huang, Y.; Liu, Z.; Wang, J.; Sun, X.; Yang, L.; Wang, D. (Aug 2014). "Surgical management of juvenile nasopharyngeal angiofibroma: analysis of 162 cases from 1995 to 2012.". Laryngoscope 124 (8): 1942-6. doi:10.1002/lary.24522. PMID 24222212.
  2. Yi, Z.; Fang, Z.; Lin, G.; Lin, C.; Xiao, W.; Li, Z.; Cheng, J.; Zhou, A.. "Nasopharyngeal angiofibroma: a concise classification system and appropriate treatment options.". Am J Otolaryngol 34 (2): 133-41. doi:10.1016/j.amjoto.2012.10.004. PMID 23332298.
  3. Klatt, Edward C. (2006). Robbins and Cotran Atlas of Pathology (1st ed.). Saunders. pp. 144. ISBN 978-1416002741.