Difference between revisions of "Bizarre parosteal osteochondromatous proliferation"
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Revision as of 11:40, 16 October 2014
| Bizarre parosteal osteochondromatous proliferation | |
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| Diagnosis in short | |
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| Synonyms | Nora lesion |
General
A distinctive osteochondromatous proliferation of hands and feet.
Population
- Young adults
- 20s-30s
Location
Hands and feet
Radiology
Marginated wide based bony growth projecting into the soft tissues[1]
Gross
- Nodule covered with glistening cartilage
Microscopic
Disorganized cellular cartilage with a blue tint and patchy ossification matures into disorganized bone. A proliferation of fibroblasts surrounds the lesion and occupies intertrabecular spaces.
DDX
- Chondrosarcoma
- Periosteal chondroma
- Osteochondroma
- Low grade parosteal osteosarcoma
Diangostic categories
- Cartilaginous neoplasms
- Osteocartilaginous neoplasms
Stains
IHC
Molecular
t(1:17)(q32;q21)[2]
Sign out
Prognosis
- Benign
- Locally aggressive
See also
References
- ↑ http://radiopaedia.org/articles/bizarre-parosteal-osteochondromatous-proliferation
- ↑ Kuruvilla, S.; Marco, R.; Raymond, AK.; Al-Ibraheemi, A.; Tatevian, N. (2011). "BizarreParosteal Osteochondromatous Proliferation (Nora's lesion) with translocation t(1;17)(q32;q21): a case report and role of cytogenetic studies on diagnosis.". Ann Clin Lab Sci 41 (3): 285-7. PMID 22075515.
Grossing article[edit] Introduction. Protocol. Protocol notes. Alternate approaches. See also. Related protocols. References. External links.