Difference between revisions of "Immune thrombocytopenic purpura"
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*Uncommon. | *Uncommon. | ||
*Usually treated with corticosteroids and splenectomy.<ref>{{Cite journal | last1 = Zhang | first1 = C. | last2 = Liu | first2 = HF. | last3 = Chen | first3 = XH. | last4 = Gao | first4 = L. | last5 = Gao | first5 = L. | last6 = Liu | first6 = Y. | last7 = Kong | first7 = PY. | last8 = Sun | first8 = AH. | last9 = Zhang | first9 = X. | title = Is splenectomy necessary for immune thrombocytopenic purpura? The role of rituximab in patients with corticosteroid resistance in a single-center experience. | journal = Clin Ther | volume = 36 | issue = 3 | pages = 385-8 | month = Mar | year = 2014 | doi = 10.1016/j.clinthera.2014.01.017 | PMID = 24594069 }}</ref> | *Usually treated with corticosteroids and splenectomy.<ref>{{Cite journal | last1 = Zhang | first1 = C. | last2 = Liu | first2 = HF. | last3 = Chen | first3 = XH. | last4 = Gao | first4 = L. | last5 = Gao | first5 = L. | last6 = Liu | first6 = Y. | last7 = Kong | first7 = PY. | last8 = Sun | first8 = AH. | last9 = Zhang | first9 = X. | title = Is splenectomy necessary for immune thrombocytopenic purpura? The role of rituximab in patients with corticosteroid resistance in a single-center experience. | journal = Clin Ther | volume = 36 | issue = 3 | pages = 385-8 | month = Mar | year = 2014 | doi = 10.1016/j.clinthera.2014.01.017 | PMID = 24594069 }}</ref> | ||
==Gross== | |||
Features:<ref name=pmid4044880/> | |||
*Typically ~ 100 grams. | |||
*+/-Prominent white nodules (AKA ''Malpighian corpuscles'') - uncommon. | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 03:21, 6 May 2014
Immune thrombocytopenic purpura, abbreviated ITP, is a rare condition.
General
- Uncommon.
- Usually treated with corticosteroids and splenectomy.[1]
Gross
Features:[2]
- Typically ~ 100 grams.
- +/-Prominent white nodules (AKA Malpighian corpuscles) - uncommon.
Microscopic
Features:[2]
- Macrophages in the red pulp (~25% of cases).
- Neutrophils in the red pulp (~67% of cases).
Images
See also
References
- ↑ Zhang, C.; Liu, HF.; Chen, XH.; Gao, L.; Gao, L.; Liu, Y.; Kong, PY.; Sun, AH. et al. (Mar 2014). "Is splenectomy necessary for immune thrombocytopenic purpura? The role of rituximab in patients with corticosteroid resistance in a single-center experience.". Clin Ther 36 (3): 385-8. doi:10.1016/j.clinthera.2014.01.017. PMID 24594069.
- ↑ 2.0 2.1 Hayes MM, Jacobs P, Wood L, Dent DM (September 1985). "Splenic pathology in immune thrombocytopenia". J. Clin. Pathol. 38 (9): 985–8. PMC 499346. PMID 4044880. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC499346/.