Difference between revisions of "Basal crypt dysplasia"
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'''Basal crypt dysplasia''', abbreviated '''BCD''', is a dysplastic change that involves the crypt bases but ''not'' the surface.<ref>{{Cite journal | last1 = Khan | first1 = S. | last2 = McDonald | first2 = SA. | last3 = Wright | first3 = NA. | last4 = Graham | first4 = TA. | last5 = Odze | first5 = RD. | last6 = Rodriguez-Justo | first6 = M. | last7 = Zeki | first7 = S. | title = Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells. | journal = J Pathol | volume = 231 | issue = 1 | pages = 98-104 | month = Sep | year = 2013 | doi = 10.1002/path.4211 | PMID = 23695891 }}</ref> | '''Basal crypt dysplasia''', abbreviated '''BCD''' or '''CD''', is a dysplastic change that involves the crypt bases but ''not'' the surface.<ref>{{Cite journal | last1 = Khan | first1 = S. | last2 = McDonald | first2 = SA. | last3 = Wright | first3 = NA. | last4 = Graham | first4 = TA. | last5 = Odze | first5 = RD. | last6 = Rodriguez-Justo | first6 = M. | last7 = Zeki | first7 = S. | title = Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells. | journal = J Pathol | volume = 231 | issue = 1 | pages = 98-104 | month = Sep | year = 2013 | doi = 10.1002/path.4211 | PMID = 23695891 }}</ref> | ||
==Microscopic== | ==Microscopic== | ||
Revision as of 14:34, 1 April 2014
Basal crypt dysplasia, abbreviated BCD or CD, is a dysplastic change that involves the crypt bases but not the surface.[1]
Microscopic
Features:
- "Dysplastic changes" in the crypt base:
- Hyperchromasia - important.
- Nuclear enlargement.
- Nuclear crowding (pseudostratification).
- Non-dysplastic (normal) surface epithelium.
See also
References
- ↑ Khan, S.; McDonald, SA.; Wright, NA.; Graham, TA.; Odze, RD.; Rodriguez-Justo, M.; Zeki, S. (Sep 2013). "Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells.". J Pathol 231 (1): 98-104. doi:10.1002/path.4211. PMID 23695891.