Difference between revisions of "Pineal gland"

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*Cellular.
*Cellular.


==Pathology==
==Overview==
Common tumours:<ref name=pmid20971711>{{cite journal |author=Gaillard F, Jones J |title=Masses of the pineal region: clinical presentation and radiographic features |journal=Postgrad Med J |volume=86 |issue=1020 |pages=597–607 |year=2010 |month=October |pmid=20971711 |doi=10.1136/pgmj.2009.087460 |url=}}</ref>
Tumours:<ref name=pmid20971711>{{cite journal |author=Gaillard F, Jones J |title=Masses of the pineal region: clinical presentation and radiographic features |journal=Postgrad Med J |volume=86 |issue=1020 |pages=597–607 |year=2010 |month=October |pmid=20971711 |doi=10.1136/pgmj.2009.087460 |url=}}</ref>
*Primary pineal tumours ~15% of (pineal) tumours.
*Primary pineal tumours ~15% of (pineal) tumours - benign to malignant:<ref name=pmid21057132>{{cite journal |author=Smith AB, Rushing EJ, Smirniotopoulos JG |title=From the archives of the AFIP: lesions of the pineal region: radiologic-pathologic correlation |journal=Radiographics |volume=30 |issue=7 |pages=2001–20 |year=2010 |month=November |pmid=21057132 |doi=10.1148/rg.307105131 |url=}}</ref>
**Pineocytoma.
**Pineocytoma.
**Pineal parenchymal tumor of intermediate differentiation.
**Pineoblastoma.
**Pineoblastoma.
*Germ cell tumours.
*Germ cell tumours:
**Germinoma ~ 50% of (pineal) tumours.
**Germinoma ~ 50% of (pineal) tumours.
**Teratoma ~ 15% of tumours.  
**Teratoma ~ 15% of tumours.  
**Choricocarcinoma ~ 5% of tumours.
**Choricocarcinoma ~ 5% of tumours.
*Others.
*Others:
**Direct invasion/extension from surrounding structures (gliomas).
**Direct invasion/extension from surrounding structures (astrocytomas).
**Metastases.
**Metastases.
**Lipomas.
**Meningiomas.
==Primary pineal tumours==
Range from benign to malignant.
==Pineocytoma==
Features:
*Cytologically benign cells (uniform size of nuclei, regular nuclear membrane, light chromatin).
*Pineocytomatous/neurocytic rosette.<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref>
**Similar to Homer-Wright rosette - neuropil centre larger.
**Rosette with a meshwork of fibers (neuropil) at the centre.


==See also==
==See also==

Revision as of 03:10, 4 December 2010

The pineal gland is thingy that is most noted for the fact that it calcifies with age.

Normal histology

See Neurohistology#Pineal gland.
  • Cellular.

Overview

Tumours:[1]

  • Primary pineal tumours ~15% of (pineal) tumours - benign to malignant:[2]
    • Pineocytoma.
    • Pineal parenchymal tumor of intermediate differentiation.
    • Pineoblastoma.
  • Germ cell tumours:
    • Germinoma ~ 50% of (pineal) tumours.
    • Teratoma ~ 15% of tumours.
    • Choricocarcinoma ~ 5% of tumours.
  • Others:
    • Direct invasion/extension from surrounding structures (astrocytomas).
    • Metastases.
    • Lipomas.
    • Meningiomas.

Primary pineal tumours

Range from benign to malignant.

Pineocytoma

Features:

  • Cytologically benign cells (uniform size of nuclei, regular nuclear membrane, light chromatin).
  • Pineocytomatous/neurocytic rosette.[3]
    • Similar to Homer-Wright rosette - neuropil centre larger.
    • Rosette with a meshwork of fibers (neuropil) at the centre.

See also

References

  1. Gaillard F, Jones J (October 2010). "Masses of the pineal region: clinical presentation and radiographic features". Postgrad Med J 86 (1020): 597–607. doi:10.1136/pgmj.2009.087460. PMID 20971711.
  2. Smith AB, Rushing EJ, Smirniotopoulos JG (November 2010). "From the archives of the AFIP: lesions of the pineal region: radiologic-pathologic correlation". Radiographics 30 (7): 2001–20. doi:10.1148/rg.307105131. PMID 21057132.
  3. Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.