Difference between revisions of "Sickle cell disease"

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==Kidney==
==Kidney==
*[[Renal medullary carcinoma]] associated with sickle cell trait (heterozygotes for the sickle cell allele).<ref name=pmid7528470>{{cite journal |author=Davis CJ, Mostofi FK, Sesterhenn IA |title=Renal medullary carcinoma. The seventh sickle cell nephropathy |journal=Am. J. Surg. Pathol. |volume=19 |issue=1 |pages=1–11 |year=1995 |month=January |pmid=7528470 |doi= |url=}}</ref>  
*[[Renal medullary carcinoma]] associated with sickle cell trait (heterozygotes for the sickle cell allele).<ref name=pmid7528470>{{cite journal |author=Davis CJ, Mostofi FK, Sesterhenn IA |title=Renal medullary carcinoma. The seventh sickle cell nephropathy |journal=Am. J. Surg. Pathol. |volume=19 |issue=1 |pages=1–11 |year=1995 |month=January |pmid=7528470 |doi= |url=}}</ref>
 
Other kidney disease associated with sickle cell disorders:<ref name=pmid7528470>{{Cite journal  | last1 = Davis | first1 = CJ. | last2 = Mostofi | first2 = FK. | last3 = Sesterhenn | first3 = IA. | title = Renal medullary carcinoma. The seventh sickle cell nephropathy. | journal = Am J Surg Pathol | volume = 19 | issue = 1 | pages = 1-11 | month = Jan | year = 1995 | doi =  | PMID = 7528470 }}</ref>
*Papillary necrosis.
*[[Nephrotic syndrome]].
*Renal [[infarction]].
*[[Pyelonephritis]].


==Femoral head==
==Femoral head==

Revision as of 19:27, 27 October 2014

Sickle cell disease, also sickle cell anemia, is a heritable haematologic disorder associated with serious pathologies.

Liver

Images

Spleen

  • It may lead to auto infarction - result in hypofunction.
    • Splenectomy have increased risk from polysaccharide encapsulated bacteria, i.e. Neisseria meningitis, Haemophilus influenzae, and Streptococcus pneumoniae.

Gallbladder

  • Pigment stones.

Kidney

Other kidney disease associated with sickle cell disorders:[2]

Femoral head

See also

References

  1. Hurtova, M.; Bachir, D.; Lee, K.; Calderaro, J.; Decaens, T.; Kluger, MD.; Zafrani, ES.; Cherqui, D. et al. (Apr 2011). "Transplantation for liver failure in patients with sickle cell disease: challenging but feasible.". Liver Transpl 17 (4): 381-92. doi:10.1002/lt.22257. PMID 21445921.
  2. 2.0 2.1 Davis CJ, Mostofi FK, Sesterhenn IA (January 1995). "Renal medullary carcinoma. The seventh sickle cell nephropathy". Am. J. Surg. Pathol. 19 (1): 1–11. PMID 7528470. Cite error: Invalid <ref> tag; name "pmid7528470" defined multiple times with different content