Difference between revisions of "Cardiac arrhythmias"
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==Microscopic== | ==Microscopic== | ||
Features - associated with ventricular fibrillation:<ref name=pmid15837088>{{Cite journal | last1 = Baroldi | first1 = G. | last2 = Silver | first2 = MD. | last3 = Parolini | first3 = M. | last4 = Pomara | first4 = C. | last5 = Turillazzi | first5 = E. | last6 = Fineschi | first6 = V. | title = Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death. | journal = Int J Cardiol | volume = 100 | issue = 3 | pages = 435-41 | month = Apr | year = 2005 | doi = 10.1016/j.ijcard.2004.10.007 | PMID = 15837088 }}</ref> | Features - associated with ventricular fibrillation:<ref name=pmid15837088>{{Cite journal | last1 = Baroldi | first1 = G. | last2 = Silver | first2 = MD. | last3 = Parolini | first3 = M. | last4 = Pomara | first4 = C. | last5 = Turillazzi | first5 = E. | last6 = Fineschi | first6 = V. | title = Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death. | journal = Int J Cardiol | volume = 100 | issue = 3 | pages = 435-41 | month = Apr | year = 2005 | doi = 10.1016/j.ijcard.2004.10.007 | PMID = 15837088 }}</ref> | ||
* | *Myofiberbreak-up (MFB) - '''key feature'''. | ||
**Fractures of the sarcomeres perpendicular to the long axis. | **Fractures of the sarcomeres perpendicular to the long axis. | ||
**Associated with square nuclei. | **Associated with square nuclei. | ||
| Line 24: | Line 24: | ||
===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image: Cardiac | Image: Cardiac myofiberbreak-up -- intermed mag.jpg | MFB - intermed. mag. (WC) | ||
Image: Cardiac | Image: Cardiac myofiberbreak-up -- high mag.jpg | MFB - high mag. (WC) | ||
Image: Cardiac | Image: Cardiac myofiberbreak-up -- very high mag.jpg | MFB - very high mag. (WC) | ||
Image: Cardiac | Image: Cardiac myofiberbreak-up -- alt - very high mag.jpg | MFB - very high mag. (WC) | ||
</gallery> | </gallery> | ||
Revision as of 03:21, 24 November 2013
Cardiac arrhythmias, especially ventricular ones, are a mechanism associated with sudden natural death.
General
Associations
- Myocardial infarction.[1]
- Hypertensive heart disease.[2]
- Commotio cordis.
- Arrhythmogenic right ventricular cardiomyopathy.
Non-cardiac
- Electrocution.
- Hyperthermia.
Microscopic
Features - associated with ventricular fibrillation:[3]
- Myofiberbreak-up (MFB) - key feature.
- Fractures of the sarcomeres perpendicular to the long axis.
- Associated with square nuclei.
Notes:
- In cases with malignant arrhythmias, as shown by cardiac monitor at the time of death, MFB is seen in multiple sections.[3]
Images
MFB - intermed. mag. (WC)
MFB - high mag. (WC)
MFB - very high mag. (WC)
MFB - very high mag. (WC)
References
- ↑ Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 293. ISBN 978-1416054542.
- ↑ Prisant LM (April 2005). "Hypertensive heart disease". J Clin Hypertens (Greenwich) 7 (4): 231–8. PMID 15860963.
- ↑ 3.0 3.1 Baroldi, G.; Silver, MD.; Parolini, M.; Pomara, C.; Turillazzi, E.; Fineschi, V. (Apr 2005). "Myofiberbreak-up: a marker of ventricular fibrillation in sudden cardiac death.". Int J Cardiol 100 (3): 435-41. doi:10.1016/j.ijcard.2004.10.007. PMID 15837088.