Difference between revisions of "Gastric heterotopia of the duodenum"

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#redirect [[Duodenum#Gastric heterotopia of the duodenum]]
'''Gastric heterotopia of the duodenum''' is a relatively common finding of the [[duodenum]].
 
==General==
*Common ~15% of cases in one series.<ref name=pmid22295146>{{Cite journal  | last1 = Terada | first1 = T. | title = Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions. | journal = Int J Clin Exp Pathol | volume = 5 | issue = 1 | pages = 46-51 | month =  | year = 2012 | doi =  | PMID = 22295146 }}</ref>
*Probably not related to [[Helicobacter pylori]].<ref name=pmid20656325>{{Cite journal  | last1 = Genta | first1 = RM. | last2 = Kinsey | first2 = RS. | last3 = Singhal | first3 = A. | last4 = Suterwala | first4 = S. | title = Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori. | journal = Hum Pathol | volume = 41 | issue = 11 | pages = 1593-600 | month = Nov | year = 2010 | doi = 10.1016/j.humpath.2010.04.010 | PMID = 20656325 }}</ref>
 
==Gross==
*Typically nodules/polyps.<ref name=pmid6840712>{{Cite journal  | last1 = Shousha | first1 = S. | last2 = Spiller | first2 = RC. | last3 = Parkins | first3 = RA. | title = The endoscopically abnormal duodenum in patients with dyspepsia: biopsy findings in 60 cases. | journal = Histopathology | volume = 7 | issue = 1 | pages = 23-34 | month = Jan | year = 1983 | doi =  | PMID = 6840712 }}</ref>
 
==Microscopic==
Features:
#Foveolar epithelium.
#Gastric glands - body-type or antral-type.
 
DDx:
*Foveolar metaplasia (isolated) - see [[chronic duodenitis]].
*Foveolar gastric-type dysplasia.<ref>{{Cite journal  | last1 = Park | first1 = do Y. | last2 = Srivastava | first2 = A. | last3 = Kim | first3 = GH. | last4 = Mino-Kenudson | first4 = M. | last5 = Deshpande | first5 = V. | last6 = Zukerberg | first6 = LR. | last7 = Song | first7 = GA. | last8 = Lauwers | first8 = GY. | title = Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia. | journal = Am J Surg Pathol | volume = 32 | issue = 4 | pages = 524-33 | month = Apr | year = 2008 | doi = 10.1097/PAS.0b013e31815b890e | PMID = 18300795 }}</ref>
 
===Images===
<gallery>
Image: Gastric heterotopia in the duodenum -- low mag.jpg | GH - low mag. (WC)
Image: Gastric heterotopia in the duodenum -- intermed mag.jpg | GH - intermed. mag. (WC)
Image: Gastric heterotopia in the duodenum -- high mag.jpg | GH - high mag. (WC)
</gallery>
www:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267485/figure/fig03/ Gastric heterotopia (nih.gov)].<ref name=pmid22295146>{{Cite journal  | last1 = Terada | first1 = T. | title = Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions. | journal = Int J Clin Exp Pathol | volume = 5 | issue = 1 | pages = 46-51 | month =  | year = 2012 | doi =  | PMID = 22295146 }}</ref>
 
==Sign out==
<pre>
DUODENUM, BIOPSY:
- SMALL BOWEL MUCOSA WITH GASTRIC (BODY-TYPE) HETEROTOPIA.
- NEGATIVE FOR SIGNIFICANT PATHOLOGY.
</pre>
 
===Alternate===
<pre>
DUODENUM, BIOPSY:
- SMALL BOWEL MUCOSA AND BRUNNER'S GLANDS WITHIN NORMAL LIMITS.
- GASTRIC HETEROTOPIA, BODY-TYPE MUCOSA.
</pre>
 
==See also==
*[[Duodenum]].
*[[Stomach]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Duodenum]]

Revision as of 12:21, 3 May 2016

Gastric heterotopia of the duodenum is a relatively common finding of the duodenum.

General

Gross

  • Typically nodules/polyps.[3]

Microscopic

Features:

  1. Foveolar epithelium.
  2. Gastric glands - body-type or antral-type.

DDx:

Images

  • GH - low mag. (WC)

  • GH - intermed. mag. (WC)

  • GH - high mag. (WC)

www:

Sign out

 DUODENUM, BIOPSY:
- SMALL BOWEL MUCOSA WITH GASTRIC (BODY-TYPE) HETEROTOPIA.
- NEGATIVE FOR SIGNIFICANT PATHOLOGY.

Alternate

DUODENUM, BIOPSY:
- SMALL BOWEL MUCOSA AND BRUNNER'S GLANDS WITHIN NORMAL LIMITS.
- GASTRIC HETEROTOPIA, BODY-TYPE MUCOSA.

See also

References

  1. ↑ 1.0 1.1 Terada, T. (2012). "Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions.". Int J Clin Exp Pathol 5 (1): 46-51. PMID 22295146.
  2. ↑ Genta, RM.; Kinsey, RS.; Singhal, A.; Suterwala, S. (Nov 2010). "Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori.". Hum Pathol 41 (11): 1593-600. doi:10.1016/j.humpath.2010.04.010. PMID 20656325.
  3. ↑ Shousha, S.; Spiller, RC.; Parkins, RA. (Jan 1983). "The endoscopically abnormal duodenum in patients with dyspepsia: biopsy findings in 60 cases.". Histopathology 7 (1): 23-34. PMID 6840712.
  4. ↑ Park, do Y.; Srivastava, A.; Kim, GH.; Mino-Kenudson, M.; Deshpande, V.; Zukerberg, LR.; Song, GA.; Lauwers, GY. (Apr 2008). "Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.". Am J Surg Pathol 32 (4): 524-33. doi:10.1097/PAS.0b013e31815b890e. PMID 18300795.
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