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Difference between revisions of "Inflammatory bowel disease"
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Inflammatory bowel disease (view source)
Revision as of 23:12, 27 December 2012
, 23:12, 27 December 2012→Specimens: +spanking
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(→Specimens: +spanking) |
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***Paneth cell distal to the splenic flexure are abnormal. | ***Paneth cell distal to the splenic flexure are abnormal. | ||
***Ulcerative colitis is often more severe distally - even in a pancolitis, as the disease starts in the rectum and progresses toward the cecum. | ***Ulcerative colitis is often more severe distally - even in a pancolitis, as the disease starts in the rectum and progresses toward the cecum. | ||
===Spanking the clinician for submitting it all in one bottle=== | |||
<pre> | |||
COLON (SITE NOT FURTHER SPECIFIED), BIOPSIES: | |||
- COLORECTAL-TYPE MUCOSA WITH PANETH CELLS, FOCAL CRYPTITIS AND CRYPT ABSCESSES, SEE COMMENT. | |||
- NEGATIVE FOR DYSPLASIA. | |||
COMMENT: | |||
Mild architectural changes, suggestive of a chronic colitis, are present. No granulomas are | |||
identified. Lymphoid aggregates with germinal centre formation are present in multiple | |||
fragments. | |||
The lamina propria has abundant plasma cells throughout the fragments; no fragments have | |||
apparent relative sparing. | |||
It is not possible to assess whether there is a mild gradient of less severe to more | |||
severe architectural changes from proximal to distal large bowel, as may be seen in | |||
individuals with ulcerative colitis. The significance of the paneth cells cannot | |||
determined as the biopsy sites are not known. | |||
The findings are compatible with inflammatory bowel disease and chronic active infectious | |||
colitides. | |||
</pre> | |||
==Microscopic== | ==Microscopic== | ||