Difference between revisions of "Ovary"
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*[[Serous cystadenoma of the ovary]]. | *[[Serous cystadenoma of the ovary]]. | ||
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*[http://www.jultrasoundmed.org/content/27/3/327/F3.expansion.html Cortical inclusion cyst (jultrasounmed.org)].<ref name=pmid18314510>{{Cite journal | last1 = Asch | first1 = E. | last2 = Levine | first2 = D. | last3 = Kim | first3 = Y. | last4 = Hecht | first4 = JL. | title = Histologic, surgical, and imaging correlations of adnexal masses. | journal = J Ultrasound Med | volume = 27 | issue = 3 | pages = 327-42 | month = Mar | year = 2008 | doi = | PMID = 18314510 }}</ref> | |||
===[[IHC]]=== | ===[[IHC]]=== | ||
Revision as of 18:18, 31 October 2012
The ovary has a wealth of pathology. It has benign tumours and malignant ones. It is a significant part of gynecologic pathology.
Normal
- Corpora albicans - pale/white body with lobulated contour.
- Involuted corpus luteum.
- Not seen pre-pubertal.
- Number increase with age.
- Ovarian follicles.
- Stroma - hyperchromatic - spindle morphology, whorling.
- If the cells have a round morphology... think about endometriosis.
Images:
Cysts
General:
- Very common.
Most common:
- Serous cystadenoma.
- Usually uniloculated.
- Morphology: ciliated, columnar.
- Mucinous cystadenoma.
- Usually multiloculated.[1]
- Memory device: multiloculated = mucinous.
- Usually multiloculated.[1]
- Endometrioma (see endometriosis).
- Simple cyst.
- Cancerous cyst (see ovarian cancer).
Notes
- Epithelium is often lost in processing - may make interpretation challenging
- Ovarian surface epithelium (previously call germinal epithelium) - covers the ovary
Ovarian surface vs. mesothelium:
- Image: ovarian surface epithelium - endojournals.org.
- Image: mesothelium - internetattitude.com.
Endometriosis
Main article: Endometriosis
Ovarian tumours
Main article: Ovarian tumours
For a very brief overview of gynecologic tumours see: Gynecologic pathology.
Benign mesothelial inclusion cyst
- AKA mesothelial inclusion cyst.
- AKA peritoneal inclusion cyst. (???)
Epidemiology
- Assoc. with previous surgery.
- May be found incidentally, e.g. during C-section.
Gross
Microscopic
Features:
- Benign mesothelium.
- Single layer of squamoid or cuboid mesothelial cells.[5]
DDx:
Image:
IHC
- CK +ve, calretinin +ve.[5]
Pregnancy luteoma
General
- Tumour of pregnancy.
- Benign.
- Regress after pregnancy; thus, conservative management.[7]
Clinical:
- Increased serum testosterone.[8]
Gross
- Solid.
- Yellow.
Images:
Microscopic
Features:
- Sheets of cells.
- Cells with eosinophilic cytoplasm, round nuclei and prominent nucleoli.
DDx:
Images:
See also
References
- ↑ IAV. 6 February 2009.
- ↑ Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC (April 2001). "Ovarian surface epithelium: biology, endocrinology, and pathology". Endocr. Rev. 22 (2): 255–88. PMID 11294827. http://edrv.endojournals.org/cgi/pmidlookup?view=long&pmid=11294827.
- ↑ ALS. 5 February 2009.
- ↑ GAG 26 Feb 2009.
- ↑ 5.0 5.1 5.2 Urbanczyk K, Skotniczny K, Kucinski J, Friediger J (2005). "Mesothelial inclusion cysts (so-called benign cystic mesothelioma)--a clinicopathological analysis of six cases". Pol J Pathol 56 (2): 81-7. PMID 16092670.
- ↑ Asch, E.; Levine, D.; Kim, Y.; Hecht, JL. (Mar 2008). "Histologic, surgical, and imaging correlations of adnexal masses.". J Ultrasound Med 27 (3): 327-42. PMID 18314510.
- ↑ Masarie, K.; Katz, V.; Balderston, K. (Sep 2010). "Pregnancy luteomas: clinical presentations and management strategies.". Obstet Gynecol Surv 65 (9): 575-82. doi:10.1097/OGX.0b013e3181f8c41d. PMID 21144088.
- ↑ Kao, HW.; Wu, CJ.; Chung, KT.; Wang, SR.; Chen, CY.. "MR imaging of pregnancy luteoma: a case report and correlation with the clinical features.". Korean J Radiol 6 (1): 44-6. PMID 15782020.