Difference between revisions of "Inflammatory bowel disease"

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Line 193: Line 193:
**Active:
**Active:
***Neutrophils:
***Neutrophils:
****Intraepithelial (cryptitis).
****Intraepithelial (cryptitis).
****Clusters in crypts (crypt abscesses).
****Clusters in crypts (crypt abscesses).
****Erosions.  
****Erosions.  
Line 199: Line 199:
***Architectural distortion.
***Architectural distortion.
***Basal plasmacytosis.
***Basal plasmacytosis.
***Foveolar metaplasia.
***Paneth cell metaplasia (distal).
**Lack of [[granulomas]].
**Lack of [[granulomas]].


Notes:
Notes:
*†Neutrophils are usually numerous in the lamina propria in minimal/mild active inflammation.
*No full wall-thickness inflammation.
*No full wall-thickness inflammation.
*Epithelial apoptosis correlated with inflammation.<ref name=pmid19958058>{{Cite journal  | last1 = Seidelin | first1 = JB. | last2 = Nielsen | first2 = OH. | title = Epithelial apoptosis: cause or consequence of ulcerative colitis? | journal = Scand J Gastroenterol | volume = 44 | issue = 12 | pages = 1429-34 | month =  | year = 2009 | doi = 10.3109/00365520903301212 | PMID = 19958058 }}</ref>
*Epithelial apoptosis correlated with inflammation.<ref name=pmid19958058>{{Cite journal  | last1 = Seidelin | first1 = JB. | last2 = Nielsen | first2 = OH. | title = Epithelial apoptosis: cause or consequence of ulcerative colitis? | journal = Scand J Gastroenterol | volume = 44 | issue = 12 | pages = 1429-34 | month =  | year = 2009 | doi = 10.3109/00365520903301212 | PMID = 19958058 }}</ref>
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