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Difference between revisions of "Germ cell tumours"
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→Yolk sac tumour: fromat
(→Yolk sac tumour: more) |
(→Yolk sac tumour: fromat) |
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===General=== | ===General=== | ||
*Rare. | *Rare. | ||
*Aggressive - especially extragonadal tumours.<ref name=pmid18767035> | *Aggressive - especially extragonadal tumours.<ref name=pmid18767035/> | ||
Epidemiology: | Epidemiology: | ||
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*Solid pattern.<ref>URL: [http://webpathology.com/image.asp?case=34&n=8 http://webpathology.com/image.asp?case=34&n=8]. Accessed on: March 8, 2010.</ref> | *Solid pattern.<ref>URL: [http://webpathology.com/image.asp?case=34&n=8 http://webpathology.com/image.asp?case=34&n=8]. Accessed on: March 8, 2010.</ref> | ||
**Vaguely resembles ''seminoma''. | **Vaguely resembles ''seminoma''. | ||
DDx: | |||
*[[Embryonal carcinoma]]. | |||
Images: | Images: | ||
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**More sensitive than AFP.<ref name=pmid20438407>{{Cite journal | last1 = Emerson | first1 = RE. | last2 = Ulbright | first2 = TM. | title = Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers. | journal = Pathology | volume = 42 | issue = 4 | pages = 344-55 | month = Jun | year = 2010 | doi = 10.3109/00313021003767355 | PMID = 20438407 }}</ref> | **More sensitive than AFP.<ref name=pmid20438407>{{Cite journal | last1 = Emerson | first1 = RE. | last2 = Ulbright | first2 = TM. | title = Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers. | journal = Pathology | volume = 42 | issue = 4 | pages = 344-55 | month = Jun | year = 2010 | doi = 10.3109/00313021003767355 | PMID = 20438407 }}</ref> | ||
*Alpha-1 AT +ve. | *Alpha-1 AT +ve. | ||
*Cytokeratin +ve. | *Cytokeratin +ve.{{fact}} | ||
==Embryonal carcinoma== | ==Embryonal carcinoma== | ||