Gynecologic cytopathology: Difference between revisions

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*"Dense" cytoplasm.
*"Dense" cytoplasm.
*Nucleus ~2X the size of an intermediate cell nucleus.
*Nucleus ~2X the size of an intermediate cell nucleus.
*Nucleoli.
**Nucleolus - '''key feature'''.
*Note:  
**Regular/smooth nuclear membrane.
**Squamous metaplastic cells have a similar appearance to parabasal cells; they cannot be differentiated on morphologic grounds.
 
**Squamous metaplastic cells have a high NC ratio - they are differentiated from HSIL via nuclear features (dark staining + irregular nuclear contour = HSIL).
Note:  
*Squamous metaplastic cells have a similar appearance to parabasal cells; they cannot be differentiated on morphologic grounds.
*Squamous metaplastic cells have a high NC ratio - they are differentiated from HSIL via nuclear features (dark staining + irregular nuclear contour = HSIL).
**Slight nuc. contour irregularies are accepted, may be darker staining.
**Slight nuc. contour irregularies are accepted, may be darker staining.


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