Difference between revisions of "Red blood cell"

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==Myospherulosis==
==Myospherulosis==
*[[AKA]] ''spherulocytosis''.<ref name=pmid7591868/>
===General===
===General===
*A round aggregrate of RBCs.
*Granulomatous reaction to fat and RBCs.<ref name=pmid11811513>{{Cite journal  | last1 = Fisher | first1 = SC. | last2 = Horning | first2 = GM. | last3 = Hellstein | first3 = JW. | title = Myospherulosis complicating cortical block grafting: a case report. | journal = J Periodontol | volume = 72 | issue = 12 | pages = 1755-9 | month = Dec | year = 2001 | doi = 10.1902/jop.2001.72.12.1755 | PMID = 11811513 }}</ref><ref name=pmid7591868/>
*Granulomatous lesion.<ref name=pmid11811513>{{Cite journal  | last1 = Fisher | first1 = SC. | last2 = Horning | first2 = GM. | last3 = Hellstein | first3 = JW. | title = Myospherulosis complicating cortical block grafting: a case report. | journal = J Periodontol | volume = 72 | issue = 12 | pages = 1755-9 | month = Dec | year = 2001 | doi = 10.1902/jop.2001.72.12.1755 | PMID = 11811513 }}</ref>
*Rare.<ref name=pmid9866916>{{Cite journal  | last1 = Sarkar | first1 = S. | last2 = Gangane | first2 = N. | last3 = Sharma | first3 = S. | title = Myospherulosis of maxillary sinus--a case report with review of literature. | journal = Indian J Pathol Microbiol | volume = 41 | issue = 4 | pages = 491-3 | month = Oct | year = 1998 | doi =  | PMID = 9866916 }}</ref>
*Rare.<ref name=pmid9866916>{{Cite journal  | last1 = Sarkar | first1 = S. | last2 = Gangane | first2 = N. | last3 = Sharma | first3 = S. | title = Myospherulosis of maxillary sinus--a case report with review of literature. | journal = Indian J Pathol Microbiol | volume = 41 | issue = 4 | pages = 491-3 | month = Oct | year = 1998 | doi =  | PMID = 9866916 }}</ref>


Etiology:
Etiology:
*Exposure to dying fat, e.g. [[fat necrosis of the breast]].
*Exposure to dying fat,<ref name=pmid7591868>{{Cite journal  | last1 = Godbersen | first1 = GS. | last2 = Kleeberg | first2 = J. | last3 = Lüttges | first3 = J. | last4 = Werner | first4 = JA. | title = [Spherulocytosis (myospherulosis) of the paranasal sinuses]. | journal = HNO | volume = 43 | issue = 9 | pages = 552-5 | month = Sep | year = 1995 | doi =  | PMID = 7591868 }}</ref></ref> e.g. [[fat necrosis of the breast]].
*Malignancy, e.g. [[renal cell carcinoma]].<ref name=pmid11035579>{{Cite journal  | last1 = Chau | first1 = KY. | last2 = Pretorius | first2 = JM. | last3 = Stewart | first3 = AW. | title = Myospherulosis in renal cell carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 10 | pages = 1476-9 | month = Oct | year = 2000 | doi = 10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2 | PMID = 11035579 }}</ref>
*Malignancy, e.g. [[renal cell carcinoma]].<ref name=pmid11035579>{{Cite journal  | last1 = Chau | first1 = KY. | last2 = Pretorius | first2 = JM. | last3 = Stewart | first3 = AW. | title = Myospherulosis in renal cell carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 10 | pages = 1476-9 | month = Oct | year = 2000 | doi = 10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2 | PMID = 11035579 }}</ref>


===Microscopic===
===Microscopic===
Features:
Features:
*Round aggregates of red blood cells ~10-20 RBCs in diameter (80-160 micrometers).
*Phagocytosed RBCs.
**Round aggregates of red blood cells ~10-20 RBCs in diameter (80-160 micrometers).


==See also==
==See also==

Revision as of 13:48, 13 April 2012

The red blood cell, abbreviated RBC, is the carrier of oxygen to tissue. It is seen daily by pathologists.

It is approximately 8 micrometers in diameter.[1]

Precursors

Reticulocyte

The direct precursor to the RBC is the reticulocyte.

Image:

Normoblast

Normoblasts are the nucleated precursors of RBCs.

Images:

Myospherulosis

General

  • Granulomatous reaction to fat and RBCs.[3][2]
  • Rare.[4]

Etiology:

Microscopic

Features:

  • Phagocytosed RBCs.
    • Round aggregates of red blood cells ~10-20 RBCs in diameter (80-160 micrometers).

See also

References

  1. URL: http://www.wisegeek.com/how-large-is-a-micrometer.htm. Accessed on: 17 January 2011.
  2. 2.0 2.1 2.2 Godbersen, GS.; Kleeberg, J.; Lüttges, J.; Werner, JA. (Sep 1995). "[Spherulocytosis (myospherulosis) of the paranasal sinuses].". HNO 43 (9): 552-5. PMID 7591868.
  3. Fisher, SC.; Horning, GM.; Hellstein, JW. (Dec 2001). "Myospherulosis complicating cortical block grafting: a case report.". J Periodontol 72 (12): 1755-9. doi:10.1902/jop.2001.72.12.1755. PMID 11811513.
  4. Sarkar, S.; Gangane, N.; Sharma, S. (Oct 1998). "Myospherulosis of maxillary sinus--a case report with review of literature.". Indian J Pathol Microbiol 41 (4): 491-3. PMID 9866916.
  5. Chau, KY.; Pretorius, JM.; Stewart, AW. (Oct 2000). "Myospherulosis in renal cell carcinoma.". Arch Pathol Lab Med 124 (10): 1476-9. doi:10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2. PMID 11035579.