Difference between revisions of "Hemophagocytic syndrome"
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Features:<ref name=pmid11076718>{{cite journal |author=Fisman DN |title=Hemophagocytic syndromes and infection |journal=Emerging Infect. Dis. |volume=6 |issue=6 |pages=601–8 |year=2000 |pmid=11076718 |pmc=2640913 |doi= |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640913/?tool=pubmed}}</ref> | Features:<ref name=pmid11076718>{{cite journal |author=Fisman DN |title=Hemophagocytic syndromes and infection |journal=Emerging Infect. Dis. |volume=6 |issue=6 |pages=601–8 |year=2000 |pmid=11076718 |pmc=2640913 |doi= |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640913/?tool=pubmed}}</ref> | ||
*Fever. | *Fever. | ||
*Splenomegaly. | *[[Splenomegaly]]. | ||
*Jaundice. | *Jaundice. | ||
Revision as of 04:54, 2 September 2010
Hemophagocytic syndrome, also known as hemophagocytic lymphohistiocytosis, is a rare condition often associated with viral infections.
Clinical
Features:[1]
- Fever.
- Splenomegaly.
- Jaundice.
Classification
Classified by etiology:[2]
- Primary, i.e. inherited.
- Secondary:
- Infection, e.g. EBV, HIV.
- Malignancy.
- Rheumatologic condition.
Microscopic
Features:[1]
- Macrophages with phagocytosed:
- Erythrocytes.
- Leukocytes.
- Platelets.
Images: HLH (WC).
See also
References
- ↑ 1.0 1.1 Fisman DN (2000). "Hemophagocytic syndromes and infection". Emerging Infect. Dis. 6 (6): 601–8. PMC 2640913. PMID 11076718. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640913/?tool=pubmed.
- ↑ Gupta S, Weitzman S (January 2010). "Primary and secondary hemophagocytic lymphohistiocytosis: clinical features, pathogenesis and therapy". Expert Rev Clin Immunol 6 (1): 137–54. PMID 20383897.