Difference between revisions of "Serrated polyposis syndrome"
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'''Hyperplastic polyposis syndrome''' is an uncommon condition characterized by the presence of (colonic) [[hyperplastic polyp]]s, may represent several distinct pathologies and is associated with an increased risk of [[colorectal carcinoma]].<ref name=pmid21045813>{{Cite journal | last1 = Huang | first1 = CS. | last2 = Farraye | first2 = FA. | last3 = Yang | first3 = S. | last4 = O'Brien | first4 = MJ. | title = The clinical significance of serrated polyps. | journal = Am J Gastroenterol | volume = 106 | issue = 2 | pages = 229-40; quiz 241 | month = Feb | year = 2011 | doi = 10.1038/ajg.2010.429 | PMID = 21045813 }}</ref> | '''Hyperplastic polyposis syndrome''' is an uncommon condition characterized by the presence of (colonic) [[hyperplastic polyp]]s, may represent several distinct pathologies and is associated with an increased risk of [[colorectal carcinoma]].<ref name=pmid21045813>{{Cite journal | last1 = Huang | first1 = CS. | last2 = Farraye | first2 = FA. | last3 = Yang | first3 = S. | last4 = O'Brien | first4 = MJ. | title = The clinical significance of serrated polyps. | journal = Am J Gastroenterol | volume = 106 | issue = 2 | pages = 229-40; quiz 241 | month = Feb | year = 2011 | doi = 10.1038/ajg.2010.429 | PMID = 21045813 | URL = http://www.nature.com/ajg/journal/v106/n2/full/ajg2010429a.html }}</ref> | ||
==WHO definition== | ==WHO definition== | ||
One of the following three:<ref name=pmid21045813>{{Cite journal | last1 = Huang | first1 = CS. | last2 = Farraye | first2 = FA. | last3 = Yang | first3 = S. | last4 = O'Brien | first4 = MJ. | title = The clinical significance of serrated polyps. | journal = Am J Gastroenterol | volume = 106 | issue = 2 | pages = 229-40; quiz 241 | month = Feb | year = 2011 | doi = 10.1038/ajg.2010.429 | PMID = 21045813 }}</ref> | One of the following three:<ref name=pmid21045813>{{Cite journal | last1 = Huang | first1 = CS. | last2 = Farraye | first2 = FA. | last3 = Yang | first3 = S. | last4 = O'Brien | first4 = MJ. | title = The clinical significance of serrated polyps. | journal = Am J Gastroenterol | volume = 106 | issue = 2 | pages = 229-40; quiz 241 | month = Feb | year = 2011 | doi = 10.1038/ajg.2010.429 | PMID = 21045813 | URL = http://www.nature.com/ajg/journal/v106/n2/full/ajg2010429a.html }}</ref> | ||
#>=Five [[hyperplastic polyp]]s proximal to the sigmoid colon with two of the five >=10 mm. | #>=Five [[hyperplastic polyp]]s proximal to the sigmoid colon with two of the five >=10 mm. | ||
#One [[hyperplastic polyp]]s proximal to the sigmoid colon, in someone with a first degree relative with the syndrome. | #One [[hyperplastic polyp]]s proximal to the sigmoid colon, in someone with a first degree relative with the syndrome. | ||
Revision as of 00:13, 14 December 2011
Hyperplastic polyposis syndrome is an uncommon condition characterized by the presence of (colonic) hyperplastic polyps, may represent several distinct pathologies and is associated with an increased risk of colorectal carcinoma.[1]
WHO definition
One of the following three:[1]
- >=Five hyperplastic polyps proximal to the sigmoid colon with two of the five >=10 mm.
- One hyperplastic polyps proximal to the sigmoid colon, in someone with a first degree relative with the syndrome.
- >30 hyperplastic polyps through-out the colon, i.e. not all can be rectal polyps.
- One source[2] suggests it ought to be >=20 HPs.
References
- ↑ 1.0 1.1 Huang, CS.; Farraye, FA.; Yang, S.; O'Brien, MJ. (Feb 2011). "The clinical significance of serrated polyps.". Am J Gastroenterol 106 (2): 229-40; quiz 241. doi:10.1038/ajg.2010.429. PMID 21045813.
- ↑ URL: http://www.hindawi.com/journals/pri/2011/157073/. Accessed on: 13 December 2011.