Difference between revisions of "An introduction to head and neck pathology"

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==Pyogenic granuloma==
==Pyogenic granuloma==
===General===
*Sometimes ''pregnancy tumour''.
*Sometimes ''pregnancy tumour''.
*Seen in children, young adults, pregnant women.
*Seen in children, young adults, pregnant women.


Histology<ref>PBoD P.775.</ref>
===Gross===
Features:<ref>PBoD P.776.</ref>
*Erythematous.
*Hemorrhagic.
 
===Microscopic===
Features:<ref>PBoD P.775.</ref>
*Vascular.  
*Vascular.  
*Peduncular lesion.
*Peduncular lesion.
Gross<ref>PBoD P.776.</ref>
*Erythematous.
*Hemorrhagic.


DDx:
DDx:
*Capillary hemangioma.
*Capillary hemangioma.


==Hairy leukoplakia==
==Hairy leukoplakia==
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*Acanthosis (thicker stratum spinosum).<ref>[http://www.emedicine.com/asp/dictionary.asp?keyword=acanthosis]</ref>
*Acanthosis (thicker stratum spinosum).<ref>[http://www.emedicine.com/asp/dictionary.asp?keyword=acanthosis]</ref>
*"Balloon cells" in upper stratum spinosum - perinuclear clearing.
*"Balloon cells" in upper stratum spinosum - perinuclear clearing.


==Plummer-Vinson syndrome==
==Plummer-Vinson syndrome==
Triad:<ref>PBoD P.776</ref>
Triad:<ref>PBoD P.776.</ref>
*Iron-deficiency anemia.
*Iron-deficiency anemia.
*Glossitis.
*Glossitis.
*Esophageal dysphagia (usually related to webs).
*Esophageal dysphagia (usually related to webs).


==Oral candidiasis==
==Oral candidiasis==
*Fungus.
*Fungus.
*May be assoc. with immunodeficiency, e.g. AIDS.
*May be associated with immunodeficiency, e.g. AIDS, organ transplant/immunosuppression.


Forms:<ref>PBoD P.777.</ref>
Forms:<ref>PBoD P.777.</ref>
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Features:<ref>http://www.nature.com/modpathol/journal/v13/n10/full/3880208a.html</ref>
Features:<ref>http://www.nature.com/modpathol/journal/v13/n10/full/3880208a.html</ref>
*Polyp with lymph channels.
*Polyp with lymph channels.


==Pharyngeal carcinoma/nasopharyngeal carcinoma==
==Pharyngeal carcinoma/nasopharyngeal carcinoma==
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Image:
Image:
*[http://commons.wikimedia.org/wiki/File:Granular_cell_tumor_%283%29_skin.jpg Granular cell tumour (WC)].
*[http://commons.wikimedia.org/wiki/File:Granular_cell_tumor_%283%29_skin.jpg Granular cell tumour (WC)].
==Olfactory neuroblastoma==
*AKA ''esthesioneuroblastoma''.
===Microscopic===
Features:
*Small round (blue) cell tumour.
==Rathke's cleft cysts==
===Microscopic===
Features:
*Lined by cuboidal or columnar epithelial +occasional goblet cells.<ref>URL: [http://www.endotext.org/neuroendo/neuroendo3/neuroendo3.html http://www.endotext.org/neuroendo/neuroendo3/neuroendo3.html]. Accessed on: 27 May 2010.</ref>
*+/-Squamous metaplasia.
Image: [http://www.endotext.org/neuroendo/neuroendo3/figures/figure11.jpg Rathke's cleft cyst (endotext.org)].
==Craniopharyngioma==
*Develop from remains of Rathke's pouch.
===Microscopic===
Features:<ref>DCHH P.184.</ref>
*Well-circumscribed or pseudoinvasive border.
*Squamoid appearance - papillary arch.
Image: [http://www.lmp.ualberta.ca/resources/pathoimages/Images-C/000p039r.jpg Craniopharyngioma (lmp.ualbera.ca)].


==Ameloblastoma==
==Ameloblastoma==
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==External links==
==External links==
*[http://education.vetmed.vt.edu/curriculum/vm8054/labs/Lab17/Lab17.htm Oral cavity histology (vetmed.vt.edu)].
*[http://education.vetmed.vt.edu/curriculum/vm8054/labs/Lab17/Lab17.htm Oral cavity histology (vetmed.vt.edu)].
 
*[http://www.endotext.org/neuroendo/neuroendo3/neuroendo3.html Endocrine pathology - pituitary (endotext.org)].


[[Category:Head and neck pathology]]
[[Category:Head and neck pathology]]
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