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Difference between revisions of "Prostate gland"
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→High-grade prostatic intraepithelial neoplasia: format
m (→Mimics: make sortable) |
m (→High-grade prostatic intraepithelial neoplasia: format) |
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*[http://commons.wikimedia.org/wiki/File:High-grade_prostatic_intraepithelial_neoplasia_high_mag.jpg HGPIN - high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:High-grade_prostatic_intraepithelial_neoplasia_high_mag.jpg HGPIN - high mag. (WC)]. | ||
===Differentiating between diagnoses=== | ====Differentiating between the diagnoses==== | ||
HGPIN vs. adenocarcinoma: | HGPIN vs. adenocarcinoma: | ||
*Glands with HGPIN have two or more distinct cells layers. | *Glands with HGPIN have two or more distinct cells layers. | ||
| Line 303: | Line 303: | ||
May need IHC (especially for cancer vs. HGPIN). | May need IHC (especially for cancer vs. HGPIN). | ||
IHC | ===IHC=== | ||
*HGPIN: AMACR +ve, p63 +ve, HMWCK +ve. | |||
*Cancer: AMACR +ve, p63 -ve, HMWCK -ve. | *Cancer: AMACR +ve, p63 -ve, HMWCK -ve. | ||
*Normal: AMACR -ve, p63 +ve, HMWCK ve+. | *Normal: AMACR -ve, p63 +ve, HMWCK ve+. | ||