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Difference between revisions of "Leiomyosarcoma"
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==IHC== | ==IHC== | ||
Features: | |||
*Positive for SMC markers. | *Positive for SMC markers. | ||
**Desmin - present in all three types of muscle. | **Desmin - present in all three types of muscle. | ||
** | **H-caldesmon. | ||
**Smooth muscle myosin. | **Smooth muscle myosin. | ||
*CD10 -ve. | |||
**May be +ve.<ref name=Ref_GP284>{{Ref GP|284}}</ref> | |||
**Some use in the context of uterine lesions -- CD10 +ve in [[endometrial stromal sarcoma]]. | |||
Others:<ref name=Ref_GP284>{{Ref GP|284}}</ref> | |||
*ER, PR, AR +ve -- 30-40% of the time. | |||
*CD117 +ve/-ve. | |||
*p53 +ve. | |||
*MIB-1 high. | |||
==See also== | ==See also== | ||