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Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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Fibroblastic/myofibroblastic tumours (view source)
Revision as of 04:49, 4 October 2011
, 04:49, 4 October 2011→Desmoid-type fibromatosis: more, images
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(→Desmoid-type fibromatosis: more, images) |
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_WMSP609>{{Ref WMSP|609}}</ref> | Features:<ref name=Ref_WMSP609>{{Ref WMSP|609}}</ref><ref>URL: [http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090717111548196 http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090717111548196]. Accessed on: 4 October 2011.</ref> | ||
* | *"Sweeping fascicles"/bundles. | ||
** | *Spindle cells with: | ||
*+/- | **Small slender nuclei. | ||
**Solid dark eosinophilic cytoplasm. | |||
*+/-Mitoses - may be abundant. | |||
*Long thin-walled vessels - parallel to one another - '''important feature'''. | |||
Notes: | |||
*Hypertrophic scar-like lesion; see also ''[[dermal scar]]''. | |||
Images: | |||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20090717111548196 Desmoid tumour (surgicalpathologyatlas.com)]. | |||
*[http://www.cheapmedicinechest.com/wp-content/uploads/2010/10/Figure-4.-Desmoid-tumor-with-fibroblastic-proliferation.png Desmoid tumour (cheapmedicinechest.com)].<ref>URL: [http://www.cheapmedicinechest.com/abdominal-pain-and-colonic-obstruction-from-an-intra-abdominal-desmoid-tumor.html http://www.cheapmedicinechest.com/abdominal-pain-and-colonic-obstruction-from-an-intra-abdominal-desmoid-tumor.html]. Accessed on: 4 October 2011.</ref> | |||
===IHC=== | ===IHC=== | ||
Features:<ref name=Ref_WMSP609>{{Ref WMSP|609}}</ref> | Features:<ref name=Ref_WMSP609>{{Ref WMSP|609}}</ref> | ||
*Beta-catenin +ve. | *Beta-catenin +ve - '''important'''. | ||
*SMA +ve ~50% of lesions. | *SMA +ve ~50% of lesions. | ||