Difference between revisions of "Pancreas"
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m (→IHC) |
(→Solid pseudopapillary tumour: mroe) |
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| Line 439: | Line 439: | ||
*Cystadenoma. | *Cystadenoma. | ||
*Cystadenocarcinoma. | *Cystadenocarcinoma. | ||
*Neuroendocrine tumour - may have cytoplasmic vacuolation, hyaline globules.<ref name=pmid18708424/> | |||
===IHC=== | ===IHC=== | ||
| Line 444: | Line 445: | ||
*Beta-catenin +ve ~100% (cytoplasmic & nuclear). | *Beta-catenin +ve ~100% (cytoplasmic & nuclear). | ||
*E-cadherin +ve ~100% (cytoplasmic), -ve (membrane); antibody dependent. | *E-cadherin +ve ~100% (cytoplasmic), -ve (membrane); antibody dependent. | ||
*CD10 +ve ~ 80% '''key'''. | *CD10 +ve ~ 80% (cytoplasmic + dot-like) '''key'''. | ||
*Synaptophysin +ve ~70%. | *Synaptophysin +ve (weak cytoplasmic) ~70%. | ||
*Progesterone receptor +ve (nuclear) '''key'''. | |||
Others: | |||
*CD56 +ve. | |||
*Chromogranin -ve. | *Chromogranin -ve. | ||
==Pancreatic intraepithelial neoplasia (PanIN)== | ==Pancreatic intraepithelial neoplasia (PanIN)== | ||