Difference between revisions of "Small cell lymphomas"
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(→Table of B-cell lymphoma: wikify) |
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| Mantle cell lymphoma | | Mantle cell lymphoma | ||
| | | mantle zone | ||
| | | small | ||
| CD5+, CD23-, CD43+, cyclin D1+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | | CD5+, CD23-, CD43+, cyclin D1+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | ||
| t(11;14)(q13;q32) BCL1/IGH<ref>URL: [http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html]. Accessed on: 10 August 2010.</ref> (also IGH/BCL1<ref>URL: [http://www.wipo.int/patentscope/search/en/WO2010059499 http://www.wipo.int/patentscope/search/en/WO2010059499]. Accessed on: 26 May 2011.</ref>) | | t(11;14)(q13;q32) BCL1/IGH<ref>URL: [http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html http://atlasgeneticsoncology.org/Anomalies/t1114ID2021.html]. Accessed on: 10 August 2010.</ref> (also IGH/BCL1<ref>URL: [http://www.wipo.int/patentscope/search/en/WO2010059499 http://www.wipo.int/patentscope/search/en/WO2010059499]. Accessed on: 26 May 2011.</ref>) | ||
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| Marginal zone lymphoma (includes MALT) | | Marginal zone lymphoma (includes MALT) | ||
| | | [[lymph node|marginal zone]], [[spleen]], GI tract | ||
| | | small | ||
| CD21+, CD11c+, CD5-, CD23-<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | | CD21+, CD11c+, CD5-, CD23-<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | ||
| t(11;18)(q21;q21) / API2‐MALT1, t(14;18)(q32;q21) / IGH‐MALT1, t(1;14)(p22;q32) / IGH‐BCL10<ref name=pmid16950858>{{cite journal |author=Bacon CM, Du MQ, Dogan A |title=Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists |journal=J. Clin. Pathol. |volume=60 |issue=4 |pages=361–72 |year=2007 |month=April |pmid=16950858 |pmc=2001121 |doi=10.1136/jcp.2005.031146 |url=}}</ref> | | t(11;18)(q21;q21) / API2‐MALT1, t(14;18)(q32;q21) / IGH‐MALT1, t(1;14)(p22;q32) / IGH‐BCL10<ref name=pmid16950858>{{cite journal |author=Bacon CM, Du MQ, Dogan A |title=Mucosa-associated lymphoid tissue (MALT) lymphoma: a practical guide for pathologists |journal=J. Clin. Pathol. |volume=60 |issue=4 |pages=361–72 |year=2007 |month=April |pmid=16950858 |pmc=2001121 |doi=10.1136/jcp.2005.031146 |url=}}</ref> | ||
| classical GI | | classical GI lymphoma | ||
| | | subtypes: extranodal marginal zone lymphoma ([[AKA]] MALT lymphoma), SMZL, nodal marginal zone lymphoma | ||
|- | |- | ||
| Precursor B cell lymphoblastic lymphoma/leukemia | | Precursor B cell lymphoblastic lymphoma/leukemia | ||
| | | location ? | ||
| | | small | ||
| CD10+, CD5-, TdT+, CD99+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | | CD10+, CD5-, TdT+, CD99+<ref name=Ref_Lester95>{{Ref Lester|95}}</ref> | ||
| t(9;22), others | | t(9;22), others | ||
| good prognosis (?) | | good prognosis (?) | ||
| | | other ? | ||
|- | |- | ||
| B cell small lymphocytic lymphoma /<br>chronic lymphocytic leukemia | | B cell small lymphocytic lymphoma /<br>chronic lymphocytic leukemia | ||
| | | location ? | ||
| Small | | Small | ||
| CD5+, CD23+, CD43+, cyclin D1- | | CD5+, CD23+, CD43+, cyclin D1- | ||
| | | translocations ? | ||
| good prognosis / indolent course | | good prognosis / indolent course | ||
| | | other ? | ||
|- <!-- | |- <!-- | ||
| Name/entity ? | | Name/entity ? | ||
| | | location ? | ||
| | | size of cells ? | ||
| IHC ? | | IHC ? | ||
| | | translocations ? | ||
| | | clinical ? | ||
| | | other ? --> | ||
|} | |} | ||
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! IHC | ! IHC | ||
! Translocations | ! Translocations | ||
! Clinical | ! Clinical | ||
! Other | ! Other | ||
|- | |- | ||
| [[Burkitt's lymphoma]] | | [[Burkitt's lymphoma]] | ||
| | | follicle | ||
| | | large cells | ||
| CD10, BCL6 | | CD10, BCL6 | ||
| t(8;14) (q24;q32) | | t(8;14) (q24;q32) | ||
| | | rapid growth | ||
| " | | "starry sky" | ||
|- | |- | ||
| [[Diffuse large B cell lymphoma]] | | [[Diffuse large B cell lymphoma]] | ||
| | | follicle (?) | ||
| Large 4-5X of lymphocyte | | Large 4-5X of lymphocyte | ||
| MIB-1 >40% | | MIB-1 >40% | ||
| none/like follicular l. | | none/like follicular l. | ||
| | | poor prognosis | ||
| | | common among lymphomas | ||
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