Difference between revisions of "Endometrial carcinoma"

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m (→‎Grading (FIGO): write-out)
m (PBoD)
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*Dyskeratosis = abnormal keratinization;<ref>[http://dictionary.reference.com/browse/dyskeratosis http://dictionary.reference.com/browse/dyskeratosis]</ref> classically have intensely eosinophilic cytoplasm +/- nuclear fragmentation ([http://dictionary.reference.com/browse/karyolysis?db=medical&q=karyolysis karyorrhexis]) - see: [http://www.drmihm.com/pictures/Figure%203.jpg several dyskeratotic cells].
*Dyskeratosis = abnormal keratinization;<ref>[http://dictionary.reference.com/browse/dyskeratosis http://dictionary.reference.com/browse/dyskeratosis]</ref> classically have intensely eosinophilic cytoplasm +/- nuclear fragmentation ([http://dictionary.reference.com/browse/karyolysis?db=medical&q=karyolysis karyorrhexis]) - see: [http://www.drmihm.com/pictures/Figure%203.jpg several dyskeratotic cells].
==Grading (FIGO)==
==Grading (FIGO)==
*Based on gland formation & adjusted by nuclear pleomorphism:<ref>PBoD P.1087-8.</ref><ref>[http://www.pathologyoutlines.com/uterus.html#endometrialcarc][http://www.emedicine.com/med/topic2832.htm][http://www.ncbi.nlm.nih.gov/pubmed/12496701]</ref>
*Based on gland formation & adjusted by nuclear pleomorphism:<ref>{{Ref PBoD|1087-8}}</ref><ref>[http://www.pathologyoutlines.com/uterus.html#endometrialcarc][http://www.emedicine.com/med/topic2832.htm][http://www.ncbi.nlm.nih.gov/pubmed/12496701]</ref>
**Grade 1: <5% solid component.  
**Grade 1: <5% solid component.  
**Grade 2: 5-50% solid component.  
**Grade 2: 5-50% solid component.  
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**IVa = bladder or bowel mucosa.
**IVa = bladder or bowel mucosa.
**IVb = distant mets (intraabdominal, inguinal nodes).
**IVb = distant mets (intraabdominal, inguinal nodes).
Ref: <ref>PBoD P.1088.</ref>, <ref>[http://www.emedicine.com/med/topic2832.htm http://www.emedicine.com/med/topic2832.htm]</ref>
Ref: <ref>{{Ref PBoD|1088}}</ref>, <ref>[http://www.emedicine.com/med/topic2832.htm http://www.emedicine.com/med/topic2832.htm]</ref>
<ref>[http://www.cancerfacts.com/GeneralContent/Uterine/Gen_Diagnosis.asp?CB=11 - Staging with groovy graphics]</ref>
<ref>[http://www.cancerfacts.com/GeneralContent/Uterine/Gen_Diagnosis.asp?CB=11 - Staging with groovy graphics]</ref>