Difference between revisions of "Rhabdomyosarcoma"

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==Molecular diagnostics==
==Molecular diagnostics==
===Alveolar rhabdomyosarcoma===
===Alveolar rhabdomyosarcoma===
Common translocations (~80%):
Common translocations (~85% of cases):
*t(1,13).
*t(1,13).
**PAX7/FKHR fusion gene.
**PAX7/FKHR fusion gene.
*t(2,13).<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/606597 http://www.ncbi.nlm.nih.gov/omim/606597]. Accessed on: 18 August 2010.</ref>
**Seen in approx. 15% of cases.
*t(2,13) ~ 70% of cases.<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/606597 http://www.ncbi.nlm.nih.gov/omim/606597]. Accessed on: 18 August 2010.</ref>
**PAX3/FKHR fusion gene.
**PAX3/FKHR fusion gene.
**Seen in approx. 70% of cases.


Notes:
Notes:
Retrieved from "https://librepathology.org/wiki/Rhabdomyosarcoma"