Difference between revisions of "Germ cell tumours"

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===Microscopic===
===Microscopic===
Features:
Features:
*Syncytiotrophoblasts:
*'''C'''ytotrophoblasts - '''key feature'''.
**Large + many irreg. or lobular hyperchromatic nuclei.
**Eosinophilic vacuolated cytoplasm (contains hCG).
*'''C'''ytotrophoblasts:
**'''C'''lear cytoplasm.
**'''C'''lear cytoplasm.
**Polygonal shaped cells in cords/masses.
**Polygonal shaped cells in cords/masses.
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*+/-Hemorrhage.
*+/-Hemorrhage.
*+/-Necrosis.
*+/-Necrosis.
*Syncytiotrophoblasts - may be absent.<ref>URL: [http://www.webpathology.com/image.asp?n=4&Case=36 http://www.webpathology.com/image.asp?n=4&Case=36]. Accessed on: 8 February 2011.</ref>
**Large + many irreg. or lobular hyperchromatic nuclei.
**Eosinophilic vacuolated cytoplasm (contains hCG).


Image(s):
Image(s):
*[http://www.webpathology.com/image.asp?case=36&n=1 Choriocarcinoma (webpathology.com)]
*[http://www.webpathology.com/image.asp?n=5&Case=36 Choriocarcinoma - low mag. (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=36&n=1 Choriocarcinoma (webpathology.com)].
*[http://www.webpathology.com/image.asp?n=4&Case=36 Choriocarcinoma (webpathology.com)].


Notes:
Notes:
Retrieved from "https://librepathology.org/wiki/Germ_cell_tumours"