Difference between revisions of "Eccrine spiradenoma"
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**These two tumors are very closely related and overlap. | **These two tumors are very closely related and overlap. | ||
**Many tumors have areas of both spiradenoma and cylindroma. | **Many tumors have areas of both spiradenoma and cylindroma. | ||
**The lobules of cylindroma are | **The lobules of cylindroma are small | ||
***more consistently discrete, | ***more consistently discrete, | ||
***show more a more consistent arrangement of the light and dark cells and are | ***show more a more consistent arrangement of the light and dark cells and are | ||
***surrounded by prominent hyaline material. | ***often surrounded by prominent hyaline material. | ||
**Individual lobules of cylindroma fit together like pieces of a puzzle. | **Individual lobules of cylindroma fit together like pieces of a puzzle. | ||
**Lobules of spiradenoma | **Lobules of spiradenoma are larger | ||
***may run together and fuse, | ***may run together and fuse, | ||
***may not have a prominent hyaline surround and | ***may not have a prominent hyaline surround and | ||
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**Spiradenoma lacks clefting artefact. | **Spiradenoma lacks clefting artefact. | ||
**Spiradenoma lacks mitoses and prominent apoptosis. | **Spiradenoma lacks mitoses and prominent apoptosis. | ||
**BCC lacks ducts | |||
**BCC lobules lack a prominent surrounding hyaline membrane | |||
*Lymphoid aggregate (spiradenoma will be cytokeratin positive) | *Lymphoid aggregate (spiradenoma will be cytokeratin positive) | ||